|1.||Kasai, Tatsuya: 3 articles (11/2009 - 08/2008)|
|2.||Fukushima, Shoji: 3 articles (11/2009 - 08/2008)|
|3.||Umeda, Yumi: 3 articles (11/2009 - 08/2008)|
|4.||Nagano, Kasuke: 3 articles (11/2009 - 08/2008)|
|5.||Aggarwal, Megha: 2 articles (01/2012 - 11/2011)|
|6.||Tomar, Shailly: 2 articles (01/2012 - 11/2011)|
|7.||Kumar, Pravindra: 2 articles (01/2012 - 11/2011)|
|8.||Kuhn, Richard J: 2 articles (01/2012 - 11/2011)|
|9.||Sasaki, Toshiaki: 2 articles (11/2009 - 09/2009)|
|10.||Arito, Heihachiro: 2 articles (11/2009 - 09/2009)|
04/01/2014 - "Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment."
11/01/2009 - "Lifetime cancer risk of humans exposed to 1,4-dioxane through drinking-water was quantitatively estimated with a non-threshold approach by application of a linearized multistage model to dose-carcinogenic response relationships, in addition to a threshold approach for estimation of the tolerable daily intake using no-observed- or lowest-observed-adverse-effect levels of the carcinogenic responses and uncertainty factors."
11/01/2009 - "Two nasal tumors occurring in the 8000 ppm-dosed groups were spontaneously rare and, thus, were attributed to 1,4-dioxane exposure. "
09/01/2009 - "Carcinogenicity and chronic toxicity of 1,4-dioxane were examined by inhalation exposure of 50 male F344 rats to 1,4-dioxane vapor at 0 (clean air), 50, 250, or 1250 ppm (v/v) for 6 h/day, 5 days/wk, and 104 wk. Survival rates of 250 and 1250 ppm-exposed groups were decreased near the end of the 2-yr exposure period, due probably to the occurrence of malignant tumors. "
01/01/2009 - "The EPA and the International Agency for Research on Cancer(IARC) classified 1,4-dioxane as a GROUP B2(probable human) carcinogen. "
03/07/2011 - "A shock tube and theoretical study on the pyrolysis of 1,4-dioxane."
03/07/2011 - "The dissociation of 1, 2 and 4% 1,4-dioxane dilute in krypton was studied in a shock tube using laser schlieren densitometry, LS, for 1550-2100 K with 56 ± 4 and 123 ± 3 Torr. "
12/28/2011 - "The pyrolysis of ethylene glycol vinyl ether (EGVE), an initial product of 1,4-dioxane dissociation, was examined in a diaphragmless shock tube (DFST) using laser schlieren densitometry (LS) at 57 ± 2 and 122 ± 3 Torr over 1200-1800 K. "
01/01/2012 - "In the present study, crystal structures of the protease domain of CP from Aura virus and its complex with dioxane were determined at 1.81 and 1.98 Å resolution respectively. "
01/01/2012 - "In the Aura virus capsid protease (AVCP)-dioxane complex structure, dioxane occupies the hydrophobic pocket on CP and structurally mimics the hydrophobic pyrollidine ring of Pro405 in the loop region of E2."
11/01/2011 - "Crystallization, high-resolution data collection and preliminary crystallographic analysis of Aura virus capsid protease and its complex with dioxane."
01/01/2012 - "Crystal structure of aura virus capsid protease and its complex with dioxane: new insights into capsid-glycoprotein molecular contacts."
|4.||Body Weight (Weight, Body)
11/01/1999 - "1,4-Dioxane is a nongenotoxic hepatocarcinogen but in our previous replicative DNA synthesis (RDS) studies with the [3H]thymidine (TdR)-technique, it failed to increase hepatocyte RDS values when given by gavage to male F344 rats as a single 2000 mg/kg body weight dose. "
01/01/1991 - "Treatment of rats with 1.0% dioxane in the drinking water for 5 days yielded no increase in liver/body weight nor induction of palmitoyl CoA oxidase, indicating that dioxane does not fit into the class of peroxisomal proliferating carcinogens. "
|5.||Dehydration (Water Stress)
06/15/2005 - "Upon dehydration at low water activities, dioxane decreases the water content at a given a(w). "
06/15/2005 - "Dioxane sorption isotherm obtained during dehydration resembles a smooth curve. "
05/01/2002 - "HClO4 in dioxane to produce principally 4beta,5alpha-diol 11 (80%) of which acetylation followed by dehydration with SOCl2 yielded 4beta,19-diacetoxy-5-ene compound 14 in good yield. "
01/01/2012 - "The dehydration/desolvation of two hydrate solvates of the pharmaceutically important compound finasteride (namely, bisfinasteride monohydrate monotetrahydrofuran and bisfinasteride monohydrate mono-1,4-dioxane) has been studied by solid-state nuclear magnetic resonance, powder X-ray diffraction, thermogravimetric analysis (including coupling with mass spectrometry) and dynamic vapour sorption. "
06/15/2005 - "This behavior suggests that the suppression in the uptake of water during dehydration may be due to a competition for water-binding sites on chymotrypsin by dioxane. "
|2.||DNA (Deoxyribonucleic Acid)
|3.||Ethylene Dibromide (1,2 Dibromoethane)
|6.||Ethyl Ether (Ether)