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Malononitrile dimer

has antithyroid activity; inhibits conversion of monoiodotyrosine to diiodotyrosine

Also Known As:

1,1,3-tricyano-2-amino-1-propene; TRIAP; U-9189

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitriles: 227
  - Malononitrile dimer: 3

Related Diseases

1.	Thyrotoxicosis 02/01/1961 - "The action of 1,1,3-tricyano-2-amino-1-propene (U-9189) on the thyroid gland of the rat and its effects in human thyrotoxicosis."
2.	Hypertrophy 08/01/1990 - "Triap induced an increase in cell-substratum adhesion and cellular hypertrophy in PC12 cells and also potentiated the adhesive actions of NGF. "
3.	Body Weight (Weight, Body) 01/01/1978 - "The drug malononitrile dimer (1,1,3-tricyano-2-amino-1-propene) was administered intraperitoneally to groups of mice at 20 mg/kg body weight, either as a single injection or as chronic 2-month injections. "

Related Drugs and Biologics

1.	Nerve Growth Factor (NGF)

Related Therapies and Procedures

1.	Injections