|1.||Miyashita, Kazuo: 17 articles (08/2015 - 11/2004)|
|2.||Hosokawa, Masashi: 15 articles (08/2015 - 11/2004)|
|3.||Maeda, Hayato: 7 articles (08/2015 - 11/2004)|
|4.||Nagao, Akihiko: 6 articles (10/2010 - 02/2004)|
|5.||Yasumoto, Takeshi: 4 articles (10/2013 - 12/2008)|
|6.||Ishikawa, Chie: 4 articles (10/2013 - 12/2008)|
|7.||Mori, Naoki: 4 articles (10/2013 - 12/2008)|
|8.||Beppu, Fumiaki: 4 articles (05/2013 - 12/2010)|
|9.||Sashima, Tokutake: 4 articles (11/2009 - 01/2007)|
|10.||Asai, Akira: 4 articles (08/2008 - 02/2004)|
11/01/2014 - "Various studies have pointed out that fucoxanthin is very effective for the treatment of cancer. "
12/01/2013 - "Cancer preventive efficacy of marine carotenoid fucoxanthin: cell cycle arrest and apoptosis."
01/01/2014 - "This study tested extracts from New Zealand seaweed Undaria pinnatifida containing fucoxanthin, in parallel with pure fucoxanthin, in nine human cancer cell lines, for anticancer activity. "
12/01/2013 - "Some studies show that this effect is selective, i.e., fucoxanthin has the capability to target cancer cells only, leaving normal physiological cells unaffected/less affected. "
01/01/2012 - "In silico study of fucoxanthin as a tumor cytotoxic agent."
|2.||Breast Neoplasms (Breast Cancer)
01/01/2015 - "Fucoxanthinol and fucoxanthin could be effective for the treatment and/or prevention of breast cancer."
01/01/2015 - "Comparative effects between fucoxanthinol and its precursor fucoxanthin on viability and apoptosis of breast cancer cell lines MCF-7 and MDA-MB-231."
07/01/2011 - "Four pure compounds were obtained, of which fucosterol (1) and fucoxanthin (4) were tested; it was found that fucoxanthin has strong antioxidant and cytotoxicity against breast cancer (MCF-7) with IC(50) = 11.5 μg/ml. The naturally highly conjugated safe compound fucoxanthin could be used as antioxidant and as an antitumor compound."
06/01/2014 - "Taken together, the current results suggest that fucoxanthinol and fucoxanthin could be potentially effective for the treatment and/or prevention of different types of cancers, including breast cancer. "
01/01/2015 - "We evaluated whether low doses of the natural carotenoid fucoxanthin and/or of its metabolite fucoxanthinol are effective against proliferation of estrogen-sensitive MCF-7 and estrogen-resistant MDA-MB-231 breast cancer cell lines. "
|3.||Body Weight (Weight, Body)
01/01/2011 - "In the 13-week oral dose study, 0, 20 or 200 mg/kg body weight of microalgal fucoxanthin oil was administered. "
05/01/2013 - "However, the suppressive effects of fucoxanthin on hepatic SCD1 and body weight gain were not observed in ob/ob mice. "
01/01/2011 - "In the micronucleus test, 500, 1,000, 2,000 mg/kg body weight of fucoxanthin oil was administered orally to mice. "
01/01/2011 - "This result suggested that the no-observed-adverse-effect level of fucoxanthin-containing oil extracted from microalga Chaetoseros sp. was 200 mg/kg body weight under the tested subchronic dose condition."
01/01/2011 - "Thus, the 50% lethal dose of microalgal fucoxanthin oil is more than 2,000 mg/kg body weight. "
04/24/2013 - "Fucoxanthin ameliorates inflammation and oxidative reponses in microglia."
04/24/2013 - "The findings in this study suggest that fucoxanthin may serve as a negative feedback regulator of inflammation and oxidative stress in BV2 cells and thereby may protect neuronal cells from neurotoxic mediators released by microglia. "
04/24/2013 - "This study tested the hypothesis that fucoxanthin, which is known to exert a variety of pharmacological properties, would ameliorate oxidative stress and inflammation in amyloid-β42 (Aβ42)-induced BV2 microglia cells. "
10/01/2005 - "The present result indicate fucoxanthin suppresses the inflammation of EIU by blocking the iNOS and COX-2 protein expression and its anti-inflammatory effect on eye is comparable with the effect of predinisolone used in similar doses."
10/01/2005 - "Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo."
04/25/2011 - "Human gastric adenocarcinoma MGC-803 cells were treated with fucoxanthin (25μM, 50μM or 75μM). "
04/25/2011 - "Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway."
11/30/2005 - "According to the experiments using the isogenic human colon adenocarcinoma cell lines, fucoxanthin failed to induce G0/G1 arrest in the p21-deficient HCT116 cells, but not in HCT116 wild-type cells. "
11/30/2005 - "The present study was designed to evaluate the molecular mechanisms of fucoxanthin against colon cancer using the human colon adenocarcinoma cell lines. "
01/01/2014 - "Compared with pure fucoxanthin, our extracts containing low level of fucoxanthin were found to be more effective in inhibiting the growth of lung carcinoma, colon adenocarcinoma and neuroblastoma. "
|3.||Blood Glucose (Blood Sugar)
|7.||Facilitative Glucose Transport Proteins (Glucose Transporter)
|9.||Non-alcoholic Fatty Liver Disease
|2.||Heterologous Transplantation (Xenotransplantation)
|3.||Photochemotherapy (Photodynamic Therapy)