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acyclovir triphosphate

Also Known As:

9-(2-hydroxyethoxymethyl)guanine triphosphate; triphosphoric acid, P-(2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl) ester

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Hypoxanthines: 1
        Guanine: 1793
        Acyclovir: 4814
        acyclovir triphosphate: 3

Experts

1.	Hanes, Jeremiah W: 1 article (08/2007)
2.	Johnson, Kenneth A: 1 article (08/2007)
3.	Parris, Deborah S: 1 article (08/2007)
4.	Zhu, Yali: 1 article (08/2007)
5.	Beadle, J R: 1 article (07/2000)
6.	Bellezza, C A: 1 article (07/2000)
7.	Cote, P J: 1 article (07/2000)
8.	Gerin, J L: 1 article (07/2000)
9.	Hornbuckle, W E: 1 article (07/2000)
10.	Hostetler, K Y: 1 article (07/2000)

Related Diseases

1.	Herpes Simplex 05/05/1990 - "The potent inhibition of herpes simplex type 1 (HSV-1) DNA polymerase by acyclovir triphosphate has previously been shown to be due to the formation of a dead-end complex upon binding of the next 2'-deoxynucleoside 5'-triphosphate encoded by the template after incorporation of acyclovir monophosphate into the 3'-end of the primer (Reardon, J. " 08/24/2007 - "We have examined the kinetics of incorporation of acyclovir triphosphate by the herpes simplex virus-1 DNA polymerase holoenzyme (Pol-UL42) and the human mitochondrial DNA polymerase using transient kinetic methods. "
2.	Hepatitis B 07/01/2000 - "Acyclovir triphosphate is a potent inhibitor of hepatitis B virus DNA polymerase, but acyclovir treatment provides no benefit in patients with hepatitis B virus infection. "

Related Drugs and Biologics

1.	DNA-Directed DNA Polymerase (Polymerases, DNA)
2.	Holoenzymes
3.	Acyclovir (Aciclovir)
4.	DNA Polymerase gamma
5.	acyclovir monophosphate