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2'-O-methylguanosine

Also Known As:

Gm19; guanosine, 2'-O-methyl

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Guanosine: 1156
        2'-O-methylguanosine: 5
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Guanosine: 1156
      - 2'-O-methylguanosine: 5
  - Ribonucleosides: 49
    - Guanosine: 1156
      - 2'-O-methylguanosine: 5

Experts

1.	Bai, Shijie: 1 article (05/2021)
2.	Li, Songhai: 1 article (05/2021)
3.	Lin, Mingli: 1 article (05/2021)
4.	Lin, Wenzhi: 1 article (05/2021)
5.	Yang, Zixin: 1 article (05/2021)
6.	Zhang, Peijun: 1 article (05/2021)

Related Diseases

1.	Disease Resistance 01/01/2023 - "Other significant SNPs, including Gm02_7,235,181 (LOD = 7.91), Gm02_7234594 (LOD = 7.61), Gm03_38,913,029 (LOD = 6.85), Gm04_46,003,059 (LOD = 6.03), Gm09_1,951,644 (LOD = 10.07), Gm10_39,142,024 (LOD = 7.12), Gm12_28,136,735 (LOD = 7.03), Gm13_16,350,701(LOD = 5.63), Gm14_6,185,611 (LOD = 5.51), and Gm19_44,734,953 (LOD = 6.02), were associated with abundant disease resistance genes, such as Glyma.02G084100, Glyma.03G175300, Glyma.04g189500, Glyma.09G023800, Glyma.12G160400, Glyma.13G064500, Glyma.14g073300, and Glyma.19G190200. "
2.	Neoplasms (Cancer) 12/01/1982 - "Urine levels of N-[9-(beta-D-ribofuranosyl)purin-6-ylcarbamoyl]-L-threonine, N6-(delta 2-isopentenyl)adenosine, and 2'-O-methylguanosine as determined by radioimmunoassay for normal subjects and cancer patients."
3.	Intestinal Diseases (Diseases, Intestinal) 05/01/2021 - "Our results revealed that the gut microbiome of 1 stranded short-finned pilot whale GM16 was dominated by Firmicutes (mainly Clostridium) and Fusobacteria; whereas that of the other pilot whale GM19 was composed of Gammaproteobacteria and Bacteroidetes (mainly Vibrio and Bacteroides, respectively), probably caused by intestinal disease and antibiotic treatment. "
4.	Breast Neoplasms (Breast Cancer) 10/14/2022 - "We found N6-methyladenosine (m6A), 2'-O-methyladenosine (Am), N1-methyladenosine (m1A), N6,2'-O-dimethyladenosine (m6Am), N1-methylguanosine (m1G), 2'-O-methylguanosine (Gm), 5-methylcytidine (m5C) and 2'-O-methylcytidine (Cm) were all decreased in early-stage breast cancer patients, and a nomogram prediction model was constructed. "
5.	Adenoma (Adenomas) 01/01/2023 - "Moreover, the levels of 2'-O-methyluridine and 2'-O-methylguanosine were lower in patients with colorectal adenomas than those in healthy controls. " 01/01/2023 - "The results showed that the concentrations of N 6-methyladenosine (m6A), N 1-methyladenosine (m1A), and 3-methyluridine (m3U) were increased in patients with CRC, whereas the concentrations of N 2-methylguanosine (m2G), 2'-O-methyluridine (Um), and 2'-O-methylguanosine (Gm) were decreased in patients with CRC, compared with the healthy controls and patients with colorectal adenomas. "

Related Drugs and Biologics

1.	N-methyladenosine
2.	Threonine (L-Threonine)
3.	Anti-Bacterial Agents (Antibiotics)
4.	2'-O-methylcytidine
5.	2'-O-methyluridine
6.	2'-O-methyladenosine
7.	7-methylguanosine
8.	5-methylcytidine
9.	3-methyluridine
10.	6-methyladenine