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asebotoxin III
isolated from Pieris japonica; RN given refers to above cpd
Also Known As:
acebotoxin III; asebotoxin I; grayanotoxane-5,610,14,16-pentol, 2,3-epoxy-,14-(2-hydroxypropanoate), (2beta,3beta,6beta,14R)-
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
asebotoxin III: 2
Related Diseases
1.
Edema (Dropsy)
02/01/1983 - "
[Pharmacological studies on the mechanisms of asebotoxin III-induced centrogenic pulmonary hemorrhagic edema in guinea pigs].
"
2.
Ischemia
01/01/1998 - "
These triphasic changes during ischemia were affected by various agents that affect the cytosolic ion milieu: the combination of asebotoxin-III and dihydroouabain (which increase intracellular Na+) caused an increase in Ca2+ levels in the final stage (phase III) with a manifestation of contracture after the reperfusion of the heart.
"
3.
Hemorrhage
02/01/1983 - "
Asebotoxin III (ATX-III), a diterpenoid isolated from the leaves of Asebi, Pieris japonica, was found to produce hemorrhage into the lungs when the toxin in a dose of 2-8 micrograms was injected into the lateral ventricle of guinea pigs under urethane anesthesia (0.8 g/kg, i.p.).
"
4.
Contracture
01/01/1998 - "
These triphasic changes during ischemia were affected by various agents that affect the cytosolic ion milieu: the combination of asebotoxin-III and dihydroouabain (which increase intracellular Na+) caused an increase in Ca2+ levels in the final stage (phase III) with a manifestation of contracture after the reperfusion of the heart.
"
Related Drugs and Biologics
1.
Urethane (Ethyl Carbamate)
2.
Diterpenes
3.
toxin III (Anemonia sulcata)
4.
dihydroouabain
Related Therapies and Procedures
1.
Anesthesia