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xanthine phosphoribosyltransferase
Also Known As:
guanine-xanthine phosphoribosyltransferase; guanosine phosphoribosyl transferase; guanosine phosphoribosyltransferase; xanthine-guanine phosphoribosyltransferase
Networked:
14
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Enzymes and Coenzymes: 1
Enzymes: 152586
Transferases: 6589
Glycosyltransferases: 784
Pentosyltransferases
xanthine phosphoribosyltransferase: 14
Experts
1.
Bückle Née Müller, Anne
: 1 article (01/2017)
2.
Kranz, Markus
: 1 article (01/2017)
3.
Schmidt, Herbert
: 1 article (01/2017)
4.
Weiss, Agnes
: 1 article (01/2017)
Related Diseases
1.
Teratocarcinoma
04/01/1984 - "
Eco.gpt, which codes for xanthine guanine phosphoribosyltransferase (XGPRT), when placed under the control of SV40 early genes regulating sequences (pSV2gpt) selects transformed teratocarcinoma cells with a low efficiency.
"
09/01/1984 - "
PCC3 mouse teratocarcinoma (TCC) stem cells were cotransfected with either the plasmid p delta C-1A or p delta C-1B carrying the chicken delta-crystallin gene, and with the plasmid pSV2gpt containing the selectable bacterial xanthine-guanine phosphoribosyltransferase (XGPRT) gene, using the calcium phosphate technique.
"
2.
Lymphoma (Lymphomas)
01/01/1983 - "
Epstein-Barr virus (EBV)-negative, Burkitt-like lymphoma-derived cells were transformed with a transducing vector (pSV2-gpt) containing the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase (XGPRT) and with a derivative of PSV2-gpt that carries the genes for the EBV-associated small RNAs on the EcoRI J fragment of B95-8 EBV DNA inserted at the unique EcoRI site (pJ-gpt).
"
07/15/1982 - "
We report here on hybridomas produced by fusion of normal C57BL/6 (B6) B cells (H-2b) to a hypoxanthine guanosine phosphoribosyl transferase (HGPRT) deficient variant of one of these lymphoma cell lines.
"
3.
Hepatocellular Carcinoma (Hepatoma)
10/15/1997 - "
1-Nitropyrene is an environmental contaminant that is mutagenic in many prokaryotic and eukaryotic systems, including the hypoxanthine-guanosine phosphoribosyl transferase (HGPRT) locus in the human hepatoma cell line HepG2.
"
07/01/1992 - "
Expression plasmids containing the human alpha 1-antitrypsin (alpha 1 AT) promoter fused to either adenine phosphoribosyltransferase (aprt) or xanthine-guanine phosphoribosyltransferase (gpt) coding sequences were sequentially introduced into APRT- HPRT- rat hepatoma cells.
"
4.
T-Cell Leukemia (Leukemia, T Cell)
10/01/1995 - "
This construct was subcloned into a mammalian expression vector which utilizes the SR alpha promoter, a hybrid promoter consisting of the SV40 early promoter with portions of the human T-cell leukemia virus type I long terminal repeat and also containing the Escherichia cloi xanthine-guanine phosphoribosyltransferase gene for selection.
"
5.
Xeroderma Pigmentosum (Kaposi's Disease)
07/01/1985 - "
Expression of a nonselectable gene (cat, coding for chloramphenicol acetyltransferase [CAT]) linked to a selectable gene (gpt, coding for xanthine-guanine phosphoribosyltransferase [XPRT]) in the plasmid pSV2catSVgpt was quantified after transfection of SV40-transformed xeroderma pigmentosum [XP20s(SV40)] and normal human [GM0637(SV40)] fibroblast cell lines.
"
Related Drugs and Biologics
1.
Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)
2.
Hypoxanthine
3.
DNA (Deoxyribonucleic Acid)
4.
Guanylate Kinases
5.
Nitrate Reductase
6.
delta-Crystallins
7.
Complementary DNA (cDNA)
8.
Chloramphenicol O-Acetyltransferase (Chloramphenicol Acetyltransferase)
9.
Tubulin
10.
Triose-Phosphate Isomerase (Triosephosphate Isomerase)