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5-methylnicotinamide
potentiates cytotoxicity of N-methyl-N-nitrosourea
Also Known As:
5-methyl-3-pyridinecarboxamide
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyridines: 88
Nicotinic Acids: 13
Niacinamide: 2223
5-methylnicotinamide: 2
Heterocyclic Acids
Nicotinic Acids: 13
Niacinamide: 2223
5-methylnicotinamide: 2
Related Diseases
1.
Ehrlich Tumor Carcinoma
01/01/1990 - "
Exposure of Ehrlich ascites tumor cells to 3-aminobenzamide for 60 min resulted in a dose-dependent increase of cellular NAD and ATP levels at a concentration range of 0.3-5 mM. In the cells exposed to 5-methylnicotinamide there was a decrease of both nucleotide levels.
"
2.
Hyperthermia
11/01/1983 - "
Two inhibitors of poly(ADP-ribose) synthetase, 5-methylnicotinamide and m-methoxybenzamide, enhanced the cytotoxicity of 42 degrees C and 45 degrees C hyperthermia in cultured Chinese hamster V79 cells.
"
Related Drugs and Biologics
1.
Poly Adenosine Diphosphate Ribose
2.
Nucleotides
3.
NAD (NADH)
4.
Ligases (Synthetase)
5.
Adenosine Triphosphate (ATP)
6.
3-aminobenzamide
7.
3-methoxybenzamide