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fosmidomycin

from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source
Also Known As:
3-(N-formyl-N-hydroxy)aminopropylphosphonic acid; FR-31564; fosfidomycin; fosmidomycin monoammonium salt; fosmidomycin monopotassium salt; fosmidomycin monosodium salt; fosmidomycin sodium salt; (3-(formylhydroxyamino)propyl)phosphonic acid, monosodium salt
Networked: 43 relevant articles (9 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jomaa, Hassan: 13 articles (02/2011 - 09/2002)
2. Wiesner, Jochen: 12 articles (02/2011 - 09/2002)
3. Kremsner, Peter G: 7 articles (06/2012 - 12/2002)
4. Hutchinson, David: 6 articles (06/2012 - 02/2003)
5. Issifou, Saadou: 6 articles (05/2007 - 12/2002)
6. Borrmann, Steffen: 6 articles (08/2006 - 12/2002)
7. Na-Bangchang, Kesara: 5 articles (09/2010 - 01/2007)
8. Matsiegui, Pierre-Blaise: 5 articles (08/2006 - 12/2002)
9. Adegnika, Ayola A: 5 articles (08/2006 - 12/2002)
10. Oyakhirome, Sunny: 4 articles (05/2007 - 11/2004)

Related Diseases

1. Malaria
2. Falciparum Malaria (Plasmodium falciparum Malaria)
3. Infection
4. Body Weight (Weight, Body)
01/01/1982 - "After i.v. administration of 10 mg/kg of body weight, [14C]-fosmidomycin was excreted mainly in the urine (about 90% of dose within 72 h); and only a little was excreted in the expired air (14CO2) and bile of rats (less than 1% of dose), which suggested the absence of enterohepatic circulation. "
08/01/2006 - "We conducted a single-arm study to improve the precision of efficacy estimates for an oral 3-day fixed-ratio combination of fosmidomycin and clindamycin at 30 and 10 mg/kg of body weight, respectively, every 12 hours for the treatment of uncomplicated P. "
09/01/2005 - "We conducted a study of 50 children with Plasmodium falciparum malaria to evaluate the safety and efficacy of consecutively shortened regimens of artesunate-fosmidomycin (1 to 2 mg/kg of body weight and 30 mg/kg of body weight, respectively; doses given every 12 hours). "
03/01/2004 - "We conducted a randomized, controlled, open-label study to evaluate the efficacy and safety of fosmidomycin combined with clindamycin (n=12; 30 and 5 mg/kg body weight every 12 h for 5 days, respectively), compared with fosmidomycin alone (n=12; 30 mg/kg body weight every 12 h for 5 days) and clindamycin alone (n=12; 5 mg/kg body weight every 12 h for 5 days) for the clearance of asymptomatic Plasmodium falciparum infections in schoolchildren in Gabon aged 7-14 years. "
11/01/2004 - "falciparum malaria in Gabon to evaluate the efficacy and safety of an oral combination of fosmidomycin-clindamycin of 30 mg/kg and 10 mg/kg of body weight, respectively, every 12 h. "
5. Bacterial Infections (Bacterial Infection)

Related Drugs and Biologics

1. Clindamycin (Cleocin)
2. artesunate
3. Gentamicins (Gentamicin)
4. Fosfomycin
5. artemisinine (artemisinin)
6. Mevalonic Acid (Mevalonate)
7. Urocortins
8. Brain Natriuretic Peptide (Natrecor)
9. Ritonavir (Norvir)
10. Lamivudine (3TC)