perillartine

RN given refers to cpd without isomeric designation

Also Known As:

perillartine, (E)-(+)-isomer; perillartine, (E)-(+-)-isomer; perillartine, (E)-(-)-isomer; perillartine, (E)-isomer; perillartine, (S)-isomer; 4-(1-methylethenyl)-1-cyclohexene-1-carboxaldehyde oxime (E)

Networked: 2 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Hydroxylamines: 16
    - Oximes: 1292
      - perillartine: 2
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Monoterpenes: 522
      - perillartine: 2
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclohexanes: 3
        Cyclohexenes: 4
        perillartine: 2

Related Diseases

1.	Fatty Liver 01/23/2023 - "Perillartine protects against metabolic associated fatty liver in high-fat diet-induced obese mice." 10/15/2022 - "By using network pharmacology and molecular docking, we analyzed the potential molecular targets and pathways through which perillartine regulates lipid metabolism and alleviates fatty liver. " 01/23/2023 - "Our results provide new information on a natural product inhibitor for RORγ and reveal that perillartine is a new candidate for the treatment of obesity and metabolic associated fatty liver disease." 01/23/2023 - "In the search for drugs to treat liver steatosis, we screened 303 natural products using HepG2 cells and discovered that perillartine derived from Perilla frutescens (L.) improved fat deposition as well as glucose homeostasis in hepatocytes. "
2.	Lipid Metabolism Disorders (Metabolism Disorders, Lipid) 10/15/2022 - "Dietary supplementation with perillartine ameliorates lipid metabolism disorder induced by a high-fat diet in broiler chickens." 10/15/2022 - "Our results suggested that perillartine may be a promising, long-lasting therapeutic molecule for modulating lipid metabolism disorders in broilers."
3.	Body Weight (Weight, Body) 01/23/2023 - "In vivo, perillartine reduced body weight gain and the fat rate, improved glucose metabolism and energy balance, and altered the gut microbial composition in mice given a high-fat diet. "
4.	Non-alcoholic Fatty Liver Disease 10/15/2022 - "In this study, we explored the effects of perillartine on lipid metabolism in broiler chickens by establishing a nonalcoholic fatty liver model induced by a high-fat diet. "
5.	Obesity 01/23/2023 - "Our results provide new information on a natural product inhibitor for RORγ and reveal that perillartine is a new candidate for the treatment of obesity and metabolic associated fatty liver disease."

Related Drugs and Biologics

1.	Glucose (Dextrose)