|1.||Dauchy, Robert T: 16 articles (04/2012 - 02/2002)|
|2.||Blask, David E: 16 articles (04/2012 - 02/2002)|
|3.||Sauer, Leonard A: 13 articles (10/2011 - 02/2002)|
|4.||Krause, Jean A: 8 articles (05/2006 - 07/2002)|
|5.||Dauchy, Erin M: 7 articles (04/2012 - 06/2004)|
|6.||Davidson, Leslie K: 6 articles (08/2009 - 06/2004)|
|7.||Brainard, George C: 4 articles (12/2009 - 07/2002)|
|8.||Lynch, Darin T: 4 articles (05/2006 - 06/2004)|
|9.||Mao, Lulu: 3 articles (04/2012 - 09/2011)|
|10.||Hill, Steven M: 3 articles (04/2012 - 09/2011)|
02/20/2015 - "Surprisingly, deletion of host 12/15-LOX alone led to increased MC38 tumor growth, in association with decreased tumor 13-HODE levels, possibly due to inhibition of 12/15-LOX activity in stroma. "
07/01/2006 - "Finally, both 13-HODE and 13-OXO were shown to be inducers of GST activity in HT-29 and HCT-116 colon tumor cells. "
06/01/2003 - "Tumor LA uptake and its metabolism to the mitogen 13-hydroxyoctadecadienoic acid (13-HODE) were also substantially higher under constant light conditions. "
09/15/2000 - "A specific decrease in LA uptake and its conversion to the mitogen 13-HODE causes the tumor growth inhibition."
09/15/1999 - "The role of 13-HODE in LA-dependent growth of solid tumors is not known. "
08/06/1992 - "These results present a novel interaction between 13-HODE and LTB4 that could have important implications in the pathogenesis of inflammation."
01/01/2013 - "These results may explain why some studies show relatively weak analgesic effects of cyclooxygenase inhibitors in UVB-induced skin inflammation, as they do not inhibit synthesis of other proalgesic lipids such as LPA 18∶1, 9-and 13-HODE and HETEs. "
05/30/1997 - "The genesis of 9- and 13-HODE seems therefore to be an important factor in the development and progression of rheuma; in addition 9-HODE was reported to be a stimulus of inflammation, comparable to leukotrienes."
07/01/2014 - "The purpose of this study was to measure changes in plasma 13-HODE + 9-HODE following a 75-km cycling bout and identify potential linkages to linoleate metabolism and established biomarkers of oxidative stress (F2-isoprostanes) and inflammation (cytokines) using a metabolomics approach. "
|3.||Hepatocellular Carcinoma (Hepatoma)
09/15/1999 - "These results provide strong evidence that 13-HODE is the mitogenic signal responsible for LA-dependent growth in hepatoma 7288CTC in vivo."
09/15/1999 - "Hepatoma 7288CTC removed LA from the arterial blood and released 13-HODE [and a small amount of 13-ketooctadecadienoic acid (KODE)] into the venous blood both in vivo and during perfusion. "
10/01/1997 - "Production of 13-HODE by the hepatomas in groups I, II, and III was 35.5 +/- 6.3, 109.6 +/- 10.6, and 196.2 +/- 34.9 ng/min/g respectively, values which also were significantly different among groups (P < 0.001). "
10/01/1999 - "Linoleic acid, via its mitogenic metabolite 13-hydroxyoctadecadienoic acid (13-HODE) is an important growth stimulant of rat hepatoma 7288CTC. "
09/15/1999 - "13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo."
04/01/2013 - "Behavioural studies investigated the contribution of 9- and 13-HODE and 15-lipoxygenase to inflammatory pain behaviour. "
01/01/2013 - "Since TRPV1 agonists such as LPA 18∶1, 9- and 13-HODE, 5- and 12-HETE were elevated in the skin, they may contribute to thermal hyperalgesia and mechanical allodynia during UVB-induced inflammatory pain. "
04/01/2013 - "This study demonstrates that, although 9- and 13-HODE can activate TRPV1 in DRG cell bodies, the evidence for a role of these lipids as endogenous peripheral TRPV1 ligands in a model of inflammatory pain is at best equivocal."
04/01/2013 - "The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms."
|5.||Colonic Neoplasms (Colon Cancer)
|5.||Linoleic Acid (Linoleate)
|7.||DNA (Deoxyribonucleic Acid)
|9.||Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)
|1.||Heterologous Transplantation (Xenotransplantation)