prostaglandin Bx

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14 relevant articles (3 outcomes, 0 trials/studies) found for this Bio-Agent

Description: phospholipase A2 inhibitor; polymeric derivative of diketo-PGB1; mean MW 2,200

Also Known As:

PGBx; poly 15-keto-PGB1; poly 15-ketoprostaglandin B1; polymeric 15-keto-PGB1; Prostaglandin Bx

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Obesity 01/01/1982 - "PGBx, a polymeric prostaglandin, in chronic doses therapeutic for hereditary diabetes and hereditary obesity in mice, produces significant increases of blood neutrophils and lymphocytes in normal mice, hereditary diabetic mice, and hereditary obese mice. " 01/01/1980 - "Dose-dependent reduction of hereditary obesity in the non-diabetic mouse by polymeric prostaglandin PGBx." 01/01/1980 - "This suggests that PGBx effects on obesity and appetite are not mediated through a blood glucose mechanism." 01/01/1979 - "A polymeric derivative of prostaglandin B1, PGBX, which reactivates phosphorylation in damaged mitochondria, is shown to normalize the high blood glucose, obesity, and excessive appetite of the hereditary diabetic mouse. " Order ALL the reference details at left...
2.	Wounds and Injuries (Trauma) 04/01/1987 - "These findings suggest that PGBx may be beneficial in the treatment of CNS ischemic injuries." Order ALL the reference details at left...
3.	Myocardial Infarction 01/01/1980 - "Clearly PGBx radically improved cardiac recovery after circulatory arrest due to VF in the presence of acute myocardial infarction. " Order ALL the reference details at left...
4.	Ischemia 08/01/1985 - "Preischemic perfusion with PGBx extended the time taken to reach 50% reduction in dP/dt following the first few seconds of ischemia. " 08/01/1985 - "PGBx had no effect on the development of intracellular acidosis during ischemia. " 08/01/1985 - "A polymeric prostaglandin (PGBx) attenuates adenine nucleotide loss during global ischemia and improves myocardial function during reperfusion." 01/01/1980 - "Myocardial recovery after ischemia: in vivo effects of PGBX, a polymeric derivative of PGB1." 01/01/1979 - "PGBx, a new polymeric derivative of PGB1, previously was shown to (a) restore oxidative phosphorylation to degraded isolated rat liver mitochondria in vitro and (b) to reverse the effects of cardiogenic ischemia in monkeys and cerebral ischemia in rabbits. " Order ALL the reference details at left...
5.	Brain Ischemia (Cerebral Ischemia) 07/01/1986 - "[Effects of polymeric prostaglandin PGBx in cerebral ischemia]" 01/01/1979 - "PGBx, a new polymeric derivative of PGB1, previously was shown to (a) restore oxidative phosphorylation to degraded isolated rat liver mitochondria in vitro and (b) to reverse the effects of cardiogenic ischemia in monkeys and cerebral ischemia in rabbits. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	prostaglandin B1
2.	Blood Glucose (Blood Sugar)
3.	prostaglandin Bx
4.	Phospholipases A2 (Phospholipase A2)
5.	Pentobarbital (Nembutal)
6.	Adenine
7.	Direction compound
8.	4-bromophenacyl bromide

Related Therapies and Procedures

1.	Ligation
2.	Oral Administration

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