|1.||Schizophrenia (Dementia Praecox)
01/01/1982 - "Comparison of efficacy of a new butyrophenone derivative, timiperone and perphenazine in schizophrenia by a multicentre controlled study."
01/01/1983 - "Comparison of efficacy of timiperone, a new butyrophenone derivative, and clocapramine in schizophrenia: a multiclinic double-blind study."
01/01/1982 - "The efficacy of timiperone in schizophrenia as compared with perphenazine was assessed in a double-blind fashion in 205 patients throughout a 12-week treatment period. "
01/01/1983 - "The efficacy and safety of timiperone, a new butyrophenone derivative, in schizophrenia as compared with haloperidol were assessed in a multi-clinic double-blind controlled study in a total of 206 patients. "
01/01/1983 - "From these results, including the analysis by stratification, it was considered that timiperone was a superior or equivalent neuroleptic in comparison with clocapramine against the negative symptoms as well as the positive ones of chronic schizophrenia, and was equally safe or safer than clocapramine."
01/01/1985 - "[Prophylactic efficacy of timiperone (Tolopelon) in vomiting caused by DDP]."
09/01/1986 - "Five patients under 45 years old given Timiperone 6 mg/day by the same method had few episodes of vomiting, but suffered from extrapyramidal symptoms. "
09/01/1989 - "[Antiemetic efficacy of intravenous timiperone in emesis induced by a 5-day-course of cisplatin]."
07/01/1988 - "As we already reported, timiperone, a new neuroleptic agent of the butyrophenone group, has a strong antiemetic effect against cisplatin (CDDP)-induced emesis. "
09/01/1986 - "[Antiemetic therapy with timiperone in cisplatin-induced vomiting]."
09/01/1986 - "We would like to propose that in antiemetic therapy with Timiperone for cisplatin-induced nausea and vomiting, a dose of 4.5 mg/day be given from two days before undergoing chemotherapy because of the cumulative effect of Timiperone."
01/01/1983 - "In the over-all safety rating, there were no significant differences between the two groups, but in accompanying symptoms and side-effects, timiperone showed significantly less tendency than clocapramine in dyskinesia, insomnia, constipation and nausea. "
01/01/1983 - "Timiperone showed a higher improvement rate than clocapramine in hallucination and disturbance of self-consciousness. "
01/01/1983 - "With regard to analysis by stratification timiperone was superior to haloperidol in improving abnormal experiences such as hallucination and delusion as well as deficiency of initiative and blunted affect. "
|1.||Drug Therapy (Chemotherapy)