thymidine 5'-triphosphate (TTP)

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1999 relevant articles (118 outcomes, 126 trials/studies) found for this Bio-Agent

Description: RN given refers to parent cpd

Also Known As:

TTP; thymidine triphosphate; 2'-deoxythymidine-5'-triphosphate; dTTP; deoxythymidine triphosphate; thymidine 5'-triphosphate, P''-(32)P-labeled; thymidine 5'-triphosphate, magnesium salt; thymidine 5'-triphosphate, trisodium salt; thymidine 5'-(tetrahydrogen triphosphate)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 25

1-Ring Heterocyclic Compounds

Pyrimidines: 281

Pyrimidine Nucleotides: 28

Thymine Nucleotides: 7

thymidine 5'-triphosphate: 1999

Nucleic Acids, Nucleotides, and Nucleosides: 1

Nucleotides: 2355

Pyrimidine Nucleotides: 28

Thymine Nucleotides: 7

thymidine 5'-triphosphate: 1999

Deoxyribonucleotides: 23

Thymine Nucleotides: 7

thymidine 5'-triphosphate: 1999

Experts

1.	Budde, Ulrich: 2 articles (07/2008 - 09/2004)
2.	Blackshear, Perry J: 2 articles (06/2007 - 02/2004)
3.	Terrell, Deirdra R: 2 articles (01/2004 - 01/2003)
4.	George, James N: 2 articles (01/2004 - 01/2003)
5.	Vesely, Sara K: 2 articles (01/2004 - 01/2003)
6.	Eckardt, Kai-Uwe: 1 article (07/2008)
7.	Jantsch, Jonathan: 1 article (07/2008)
8.	Hagel, Stefan: 1 article (07/2008)
9.	Honsová, E: 1 article (07/2008)
10.	Kalden, Joachim R: 1 article (07/2008)

Related Diseases

1.	Thrombotic Thrombocytopenic Purpura 11/09/1991 - "A controlled multicentre trial was conducted in France over a period of five years in 40 patients with thrombotic thrombocytopenic purpura (TTP) to try to determine the best treatment of this disease. " 06/01/2003 - "Thrombotic thrombocytopenic purpura (TTP) is a serious hematologic disorder with a high rate of morbidity and mortality when it fails to go into remission. " 05/01/1990 - "The observation of two clinical cases make possible an evaluation of the potential therapeutic activity of platelet function inhibitors in thrombotic thrombocytopenic purpura (TTP). " 01/01/2006 - "New developments in the understanding of thrombotic thrombocytopenic purpura (TTP) provide opportunities for improved patient care. " 07/01/1993 - "In this study we evaluated the effect of serum collected from seven thrombotic thrombocytopenic purpura (TTP) patients, either in the acute phase of the disease or in clinical remission, on the in vitro growth of bone marrow haematopoietic progenitor cells, obtained from the same TTP patients in clinical remission and from normal donors. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 11/20/2008 - "RESULTS: The presence of KIT exon 11-mutant genotype (n = 283) correlated with improved treatment outcome when compared with KIT exon 9-mutant (n = 32) and wild-type (WT; n = 67) genotypes for objective response (complete response [CR]/partial response [PR], 71.7% v 44.4% [P = .007]; and 44.6% [P = .0002], respectively); time to tumor progression (TTP; median 24.7 months v 16.7 and 12.8 months, respectively); and overall survival (OS; median 60.0 months v 38.4 and 49.0 months, respectively). " 03/01/1993 - "Patients whose malignant neoplasms were in complete or partial remission at the time of development of C-TTP/HUS had a significantly higher estimated 1-year survival rate (74%) as compared with a historic control group of patients receiving other treatments (22%, P = 0.0161). " 11/01/2005 - "The median remission time was 3.5 months and time to tumor progression (TTP) was 4.5 months. " 12/01/2004 - "The time to tumor progression (TTP) was 2 to 18 months (median 5 months), and duration of remission was 4 to 14 months (median 8 months). " 09/01/2009 - "Acceptance of PFS and TTP improvement demonstrated by well designed and conducted studies as direct evidence of clinical benefit will accelerate cancer drug development and make effective therapy available to patients with cancer sooner. " Order ALL the reference details at left...
3.	Hemolytic-Uremic Syndrome 05/01/2002 - "STUDY DESIGN AND METHODS: The activities of vWF-CPase and its inhibitor were measured in 27 patients with nonfamilial TTP and hemolytic-uremic syndrome (HUS) to examine the relationship between the clinical variables and vWF-CPase activity. " 04/15/2009 - "We analyzed data from the Oklahoma TTP-HUS (hemolytic uremic syndrome) Registry, an inception cohort of 362 consecutive patients, for 1989-2007. " 04/01/2008 - "METHODS: Patient data are from The Oklahoma TTP-hemolytic uremic syndrome (HUS) Registry, an inception cohort of 348 consecutive patients with their first episode of clinically diagnosed TTP or HUS, 1989-2006. " 07/01/2007 - "The Oklahoma Thrombotic ThrombocytopenicPurpura-Hemolytic Uremic Syndrome (TTP-HUS) Registry has enrolled all 335 consecutive patients from central, western and southeastern Oklahoma who had their first episode of clinically diagnosed TTP or HUS from 1989 through 2005; follow-up is complete for 333 patients. " 01/01/2007 - "PATIENTS AND METHODS: We report the 17-year experience of The Oklahoma TTP-Hemolytic-Uremic Syndrome (HUS) Registry (1989-2005) and a systematic review of previously published case reports. " Order ALL the reference details at left...
4.	Syndrome 07/01/1990 - "All patients improved quickly following this change in therapy, and the TTP syndrome resolved in all seven." 01/01/2008 - "The study demonstrates that while differentiating between HUS and TTP is sometimes difficult, in most cases the two syndromes have quite different predisposing factors and clinical parameters, enabling clinical and epidemiological profiling for these disorders." 01/01/1979 - "The results of this study raise the possibility that TTP may fit within the myeloproliferative category, perhaps representing an acute variant of Di-Guglielmo Syndrome." 10/01/2009 - "TTP may be difficult to distinguish from haemolytic uraemic syndrome (HUS) because of similar clinical manifestations and laboratory findings. " 02/01/2009 - "Recent data support an understanding of TTP/HUS as a heterogeneous syndrome with variable mortality, and with specific subgroups demonstrating an excellent outcome." Order ALL the reference details at left...
5.	Neoplasm Metastasis (Metastasis) 07/01/2008 - "Multivariate analysis was most notable for a significantly greater OS (HR=0.49, P=0.04) and TTP (HR=0.3, P=0.01) associated with peritoneal metastases. " 05/01/2009 - "First-line treatment and non-visceral metastases were associated with longer TTP. " 06/01/2008 - "The variables that were shown to have independent predictive value for the TTP were: non-visceral metastatic disease, single metastases, hormonal receptor positive N/T ratio<2 and disease-free interval (DFI) > or = 24 months. " 11/01/2003 - "The median TTP (time to progression) for patients with liver metastases alone was also longer compared with the liver plus other sites of metastases group in both trials: 10.2 versus 8.8 months (log rank test, P=0.02) in trial 10923 and 8.3 versus 6.7 months (log rank test, P=0.37) in trial 10961. " 09/10/2009 - "We correlated AQUA LOX expression with time to metastasis (TTM), time to progression (TTP), and overall survival (OS). " Order ALL the reference details at left...

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Related Therapies and Procedures

1.	Plasma Exchange
2.	Drug Therapy (Chemotherapy)
3.	Splenectomy
4.	Plasmapheresis
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