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Collins' solution

solution resembling intracellular fluid used in perfusion of tissues or organs prior to freezing; contains 330mOsm./L.; other components listed in Urology; C-2 has high potassium content 1980;15(5):480
Also Known As:
Collin's C-2; Collin's solution; Collins-3 solution
Networked: 24 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Related Diseases

1. Hypothermia
2. Paralysis (Palsy)
09/01/1989 - "In 21 of selected relaxed heart models the energy phosphate pattern as an index of viability was measured by P-31 MRS on a 4.7 Tesla NMR tomograph in 37 experimental runs with the following perfusion protocols: 1) immediate cardioplegia with cold Bretschneider or Collins solution, transportation under cooling, MRS after approximately 1 h; 2) immediate cardioplegia, transportation, reperfusion with oxygenated warm blood, MRS; 3) immediate blood perfusion with genuine fresh arterial blood from the slaughterhouse, cold plegia perfusion, transportation, MRS; 4) immediate blood perfusion with transportation MRS; 4) immediate blood perfusion with genuinefresh arterial blood, cold plegia perfusion, transportation, reperfusion with oxygenated warm blood, MRS during reperfusion; 5) An experimental pig heart was made plegic in vivo and reperfused with oxygenated warm blood during MRS as reference.(ABSTRACT TRUNCATED AT 250 WORDS)"
01/01/1991 - "The aim of this study was to develop and test a new and simple kidney perfusion model from slaughterhouse swine using a new 4.7-tesla/40-cm diameter system, with the intention behind to provide a human-like mammalian experimental kidney perfusion model, and to avoid sensitive in vivo animal experiments on higher-developed mammalians, 35 pig kidneys obtained 10-15 min post mortem were studied to evaluate and define conditions for optimum metabolic preservation with the following perfusion protocols: (1) immediate plegia with cold Collins solution, 1-3 h cold storage, P-31 MRS; (2) immediate plegia, 1-3 h cold storage, blood reperfusion, P-31 MRS; (3) immediate blood reperfusion, plegia, 1-3 h cold storage, blood reperfusion, P-31 MRS; (4) immediate blood reperfusion, plegia, 24 h cold storage, blood reperfusion, P-31 MRS, P-31 MRS at 81 MHz with a double-tuned surface coil yielded the following results: [table: see text] Blood flow showed a weak correlation with beta-ATP/inorganic phosphate in protocols 3 and 4 of r = 0.64. "
3. Ischemia
4. Flushing
5. Heart Arrest (Cardiac Arrest)

Related Drugs and Biologics

1. Adenosine Triphosphate (ATP)
2. Sodium
3. Potassium
4. Cardioplegic Solutions
5. Lactic Acid
6. Calcium
7. Adenine
8. Citric Acid (Citrate)
9. Streptozocin (Streptozotocin)
10. Bovine Serum Albumin

Related Therapies and Procedures

1. Transplants (Transplant)
2. Induced Heart Arrest (Cardioplegia)
3. Heart-Lung Transplantation
4. Kidney Transplantation
5. Transplantation (Transplant Recipients)