6-carboxyfluorescein (carboxyfluorescein)

originally sold as 6-carboxyfluorescein, but commercial product is a mixture of two isomers; correct name is 5(6)-carboxyfluorescein
Also Known As:
carboxyfluorescein; 5(6)-carboxyfluorescein; 3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-6-carboxylic acid
Networked: 86 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Lee, Ji Hoon: 1 article (12/2014)
2. Cha, Timothy: 1 article (12/2014)
3. Cho, Sandy: 1 article (12/2014)
4. Kim, Young Teck: 1 article (12/2014)
5. Diaz Flaqué, M C: 1 article (08/2014)
6. Paulazo, M A: 1 article (08/2014)
7. Colombo, L: 1 article (08/2014)
8. Sterle, H A: 1 article (08/2014)
9. Cayrol, F: 1 article (08/2014)
10. Medina, V A: 1 article (08/2014)

Related Diseases

1. Pterygium
2. Melanoma (Melanoma, Malignant)
3. Neoplasms (Cancer)
4. Blister (Bulla)
5. Hepatocellular Carcinoma (Hepatoma)
08/01/2011 - "Flow cytometry of HCV-infected carboxyfluorescein succinimidyl ester-labeled hepatoma cells indicated a slowdown in proliferation that correlated with abundance of viral antigen. "
06/01/2009 - "So, by CLSM, we demonstrated that artificial virus-like envelope (AVE) vesicles labeled with rhodamine-PE (Rh-PE), carbocyanine (DiI) and carboxyfluorescein (CF) were investigated into the cytoplasm of two human cell lines, Mewo (human melanoma cell line) and HepG2 (human hepatoma cell line) cells grown in DMEM medium supplemented with different percentages (0%, 30%, and 100%) fetal calf serum (FCS). "
12/01/2012 - "Observations from FACS and confocal microscopic analyses revealed that rHDL-mediated carboxyfluorescein tagged Chol-siRNA (FAM-Chol-siRNA) transfection resulted in highly efficient uptake and specific cytoplasmic delivery of FAM-Chol-siRNA into human hepatocellular carcinoma cell line HepG2 via HDL-receptor mediated mechanism. "
01/01/1995 - "Two quantitative cytotoxicity assay methods (cytoplasmic retention of carboxyfluorescein and mitochondrial cleavage of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT)) have been used to evaluate the response of two cultured human cell lines; HepG2 (hepatoma) and W138va13 (transformed lung fibroblasts) to extracts of a range of poly(vinyl chloride) (PVC) formulations. "
11/16/1979 - "We studied the in vitro interaction between Zajdela ascites hepatoma cells and small unilamellar vesicles, consisting of 14C-labeled phosphatidylacholine, cholesterol, and phosphatidylserine (molar ratio 5 : 4 : 1), containing high intravesicular concentrations of carboxyfluorescein or fluorescein isothiocyanate tagged dextran. "

Related Drugs and Biologics

1. 2',7'- bis- (2- carboxyethyl)- 5(6)- carboxyfluorescein acetoxymethyl ester
2. Liposomes (Liposome)
3. Cholesterol
4. 5-(6)-carboxyfluorescein diacetate succinimidyl ester (CFSE)
5. fluorescein isothiocyanate dextran
6. Bromodeoxyuridine (BrdU)
7. Antigens
8. Fluorescent Dyes (Fluorescent Probes)
9. DNA (Deoxyribonucleic Acid)
10. Carbon Monoxide

Related Therapies and Procedures

1. Photochemotherapy (Photodynamic Therapy)
2. Fluid Therapy (Oral Rehydration Therapy)
3. Lasers (Laser)
4. Heterologous Transplantation (Xenotransplantation)
5. Microspheres (Microsphere)