daurisoline

10/01/2020 - "This study reveals that daurisoline could be a promising therapeutic strategy for the treatment of lung cancer."
10/01/2020 - "We demonstrated for the first time that daurisoline, a constituent of Rhizoma Menispermi, repressed lung cancer cell proliferation by inducing cell cycle arrest at the G1 phase. "
12/01/2022 - "Daurisoline can suppress the development of liver and lung cancers, but its effect on bladder cancer has not been investigated. "
10/01/2020 - "Direct targeting of HSP90 with daurisoline destabilizes β-catenin to suppress lung cancer tumorigenesis."
06/18/2021 - "A wide range of natural products can be considered promising anti-COVID-19 or anti-lung cancer agents have gained widespread attention, including natural products as monotherapy for the treatment of SARS-CoV-2 (ginkgolic acid, shiraiachrome A, resveratrol, and baicalein) or lung cancer (daurisoline, graveospene A, deguelin, and erianin) or in combination with FDA-approved anti-SARS-CoV-2 agents (cepharanthine plus nelfinavir, linoleic acid plus remdesivir) and anti-lung cancer agents (curcumin and cisplatin, celastrol and gefitinib). "

11/01/2021 - "This study aimed to elucidate the potential anticancer effect of daurisoline (DS) on hepatocellular carcinoma (HCC) and the potential molecular mechanism by which DS inhibits VM. "
01/01/2021 - "Daurisoline inhibits hepatocellular carcinoma progression by restraining autophagy and promoting cispaltin-induced cell death."
11/01/2021 - "The role of daurisoline treatment in hepatocellular carcinoma: Inhibiting vasculogenic mimicry formation and enhancing sensitivity to sorafenib."

12/01/2022 - "This study probed into the mechanism underlying the effects of daurisoline on angiogenesis and epithelial-mesenchymal transition (EMT) in bladder cancer. "
12/01/2022 - "Daurisoline can suppress the development of liver and lung cancers, but its effect on bladder cancer has not been investigated. "
12/01/2022 - "Daurisoline Inhibiting Tumor Angiogenesis and Epithelial-Mesenchymal Transition in Bladder Cancer by Mediating HAKAI Protein Stability."
12/01/2022 - "Daurisoline suppresses EMT and angiogenesis in bladder cancer by targeting HSP90 and disrupting the stability of HAKAI protein to up-regulate the expression of E-cad."
12/01/2022 - "Daurisoline or geldanamycin inhibited EMT of bladder cancer cells and HUVEC angiogenesis. "

10/01/2020 - "Furthermore, daurisoline was found not only to suppress the growth of lung tumor xenografts in animals without obvious side effects, but also to inhibit cell migration and invasion. "
12/01/2022 - "Daurisoline Inhibiting Tumor Angiogenesis and Epithelial-Mesenchymal Transition in Bladder Cancer by Mediating HAKAI Protein Stability."
11/24/2021 - "Finally, the combination treatment mediated by nanodrugs loaded with daurisoline and indocyanine green was more efficient than the individual modalities, resulting in complete inhibition of tumor growth. "
01/01/2022 - "Daurisoline (DAS) is a component of traditional Chinese herb, which exhibits anti-cancer effects by autophagy inhibition and metastasis suppression. "
11/24/2021 - "To identify a more effective autophagy inhibitor, we screened a library of 20 compounds and found chloroquine, hydroxychloroquine, dauricine, and daurisoline were more efficient than the others to improve the photothermal killing of cancer cells. "

10/01/2020 - "Direct targeting of HSP90 with daurisoline destabilizes β-catenin to suppress lung cancer tumorigenesis."