Sofradex

ear drop combination containing Soframycin (framycetin sulfate), gramicidin & dexamethasone

Also Known As:

Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-, mixt. with O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1->4)-O-(O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-beta-D-ribofuranosyl-(1->5))-2-deoxy-D-streptamine sulfate (1:3) (salt) and gramicidin

Networked: 4 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Back, G: 1 article (02/2005)
2.	Coatesworth, A P: 1 article (02/2005)
3.	England, R J A: 1 article (02/2005)
4.	Nadig, S K: 1 article (02/2005)
5.	Sharma, R: 1 article (02/2005)
6.	Uppal, S: 1 article (02/2005)
7.	Kent, S E: 1 article (08/2003)
8.	Lancaster, J: 1 article (08/2003)
9.	Mathews, J: 1 article (08/2003)
10.	Thussey, C: 1 article (08/2003)

Related Diseases

1.	Otitis Media with Effusion 02/01/2005 - "To compare the efficacy of 5% NaHCO3, 3% H2O2, Sofradex (dexamethasone sodium metasulphobenzoate 0.05%, framycetin sulphate 0.5%, gramicidin 0.005%), 0.33% acetic acid and 0.9% NaCl eardrops in clearing grommets blocked with harvested thick middle ear effusion fluid. "
2.	Otitis Externa 01/01/1990 - "A general practice study to compare the efficacy and tolerability of a spray ('Otomize') versus a standard drop formulation ('Sofradex') in the treatment of patients with otitis externa." 08/01/2003 - "Patients receiving Gentisone HC, Sofradex and Otomize for chronic suppurative otitis media and otitis externa were investigated for compliance of medication. " 01/01/1990 - "In an open, multi-centre study in general practice, a comparison was made of the efficacy, tolerability and acceptability of a neomycin/dexamethasone preparation administered by metered-dose spray ('Otomize') and a framycetin/gramicidin/dexamethasone preparation ('Sofradex') administered as drops in 60 patients with otitis externa. " 01/01/1985 - "In a randomized trial, 55 patients with acute external otitis were treated with either topical framycitin/gramicidin (Sofradex) or oxytetracycline/hydrocortisone (Terracortril) with polymyxin B (TPB) ear-drops for 1 week. "
3.	Suppurative Otitis Media 08/01/2003 - "Patients receiving Gentisone HC, Sofradex and Otomize for chronic suppurative otitis media and otitis externa were investigated for compliance of medication. "

Related Drugs and Biologics

1.	Gramicidin (Gramicidin A)
2.	Framycetin (Framycetin Sulfate)
3.	Dexamethasone (Maxidex)
4.	Acetic Acid (Vinegar)
5.	Sodium
6.	Saline Solution
7.	Otomize
8.	Polymyxin B (Aerosporin)
9.	Oxytetracycline (Terramycin)
10.	Neomycin

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