podorhizol
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Description:
a dibenzylbutyrolactone found in PODOPHYLLIN; RN & N1 from 9th CI Form Index; RN given refers to (3 alpha(R*),4 beta)-isomer; cpd not in Chemline 7/19/83; structure in first source;
Also Known As:
podorhizol, (3alpha(S*),4beta)-(+-)-isomer; (3 alpha(R*),4 beta)-(+-)-4-(1,3-benzodioxol-5-ylmethyl)-dihydro-3-(hydroxy(3,4,5-trimethoxyphenyl)methyl)-2(3H)-furanone
Bio-Agent Context: Research Results
Related Diseases
| 1. | Lymphoid Leukemia
02/01/2004
- " Bioassay (P388 lymphocytic leukemia cell line and human tumor cell lines)-guided separation of the extracts prepared from the tropical and coastal trees Hernandia peltata (Malaysia) and Hernandianymphaeifolia (Republic of Maldives) led to the isolation of a new lignan designated as hernanol (1) and 12 previously known lignans: (-)-deoxypodophyllotoxin (2), deoxypicropodophyllin (3), (+)-epiaschantin (4), (+)-epieudesmin (5), praderin (6), 5'-methoxyyatein (7), podorhizol (8), deoxypodorhizone (9), bursehernin (10), kusunokinol (11), clusin (12), and (-)-maculatin (13)"
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