bovine trypsin inhibitor; RN given refers to parent cpd; structure
Also Known As:
acetamidine hydrochloride; acetamidine monoacetate; acetamidine monohydrochloride; acetamidine sulfate (1:1); acetamidinium
Networked: 18 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Guo, Jin Sheng: 2 articles (05/2006 - 12/2004)
2. Koo, Marcel Wing Leung: 2 articles (05/2006 - 12/2004)
3. McCluskie, Kerryn: 2 articles (11/2004 - 03/2003)
4. Belvisi, Maria G: 2 articles (11/2004 - 03/2003)
5. Birrell, Mark A: 2 articles (11/2004 - 03/2003)
6. Yang, Mei-Juan: 1 article (05/2012)
7. Yan, Min: 1 article (05/2012)
8. Qian, Ling-Bo: 1 article (05/2012)
9. Chen, Gang: 1 article (05/2012)
10. Yu, Jing: 1 article (05/2012)

Related Diseases

1. Neuroblastoma
2. Glioma (Gliomas)
3. Myocardial Infarction
4. Ischemia
5. Inflammation
01/01/2000 - "The purpose of this study was to examine the role of NO via inducible NO synthase (iNOS) in allergic airway inflammation using a selective iNOS inhibitor, N-[3-(aminomethyl)benzyl] acetamidine (1400W), in ovalbumin (OVA)-sensitized Balb/c mice. "
11/01/2004 - "The aim was, using pharmacological tools, to determine the role of NO in an aerosolized LPS-driven animal model of airway inflammation by assessment of ex-NO, neutrophilia, and inflammatory biomarkers, using a nonselective NOS inhibitor, N(G)-nitro-l-arginine methyl ester (l-NAME), and a selective inducible NOS (iNOS) inhibitor, N-3 (aminomethyl)benzyl)acetamidine (1400W). "
01/15/2001 - "It was found that in the carrageenin-induced pleurisy, a single intrapleural injection of the selective inducible NO inhibitors S-(2-aminoethyl) isothiourea (AE-ITU; 3 and 10 mg/kg) and N-(3-(aminomethyl)-benzyl) acetamidine (1400W; 10 mg/kg) or the selective endothelial cell NOS inhibitor L-N(5)(1-iminoethyl)-ornithine (10 mg/kg) not only exacerbated inflammation at the very early stages of the lesion (1-6 h), but also prevented inflammatory resolution. "
10/01/2008 - "Using a potent selective inducible nitric oxide (NO) synthase inhibitor, N-[3-(aminomethyl) benzyl]acetamidine (1400W), and a nonselective NO synthase inhibitor, N(G)-nitro-L-arginine methyl ester (L-NAME), we investigated whether inducible NO synthase plays any role in producing hepatic injury, inflammation, and changes of protein expression following trauma-hemorrhage. "
03/01/2003 - "In this rat study, the nonselective NOS inhibitor L-NAME (N(G)-nitro-L-arginine methyl ester), but not a selective inducible NOS (iNOS) inhibitor 1400W (N-3-(aminomethyl)benzyl)acetamidine), impacted on Sephadex-induced inflammation by significantly inhibiting lung edema, eosinophil infiltration, tumor necrosis factor alpha, interleukin-13, and eotaxin levels in the lung tissue. "

Related Drugs and Biologics

1. Guanidine (Guanidine Nitrate)
2. Artificial Membranes (Artificial Membrane)
3. Gramicidin (Gramicidin A)
4. Sodium
5. Adenosine Triphosphate (ATP)
6. sevoflurane (Ultane)
7. NG-Nitroarginine Methyl Ester (L-NAME)
8. Nitric Oxide Synthase (NO Synthase)
9. Interleukin-13
10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

Related Therapies and Procedures

1. Resuscitation
2. Injections