|1.||Asano, Yasuhisa: 4 articles (01/2015 - 01/2004)|
|2.||Hashimoto, Yoshiteru: 4 articles (02/2013 - 08/2003)|
|3.||Oinuma, Ken-Ichi: 4 articles (02/2013 - 08/2003)|
|4.||Kobayashi, Michihiko: 4 articles (02/2013 - 08/2003)|
|5.||Kitagawa, Teizo: 4 articles (12/2006 - 06/2004)|
|6.||Ohta, Takehiro: 3 articles (02/2013 - 06/2004)|
|7.||Kato, Yasuo: 3 articles (12/2006 - 01/2004)|
|8.||Higashibata, Hiroki: 3 articles (11/2004 - 08/2003)|
|9.||Konishi, Kazunobu: 3 articles (11/2004 - 08/2003)|
|10.||Tekes, Kornélia: 2 articles (05/2009 - 08/2007)|
|1.||Parkinsonian Disorders (Parkinsonism)
01/01/2003 - "Although acute cholinergic crisis was treated successfully with large doses of atropine and 2-pyridine aldoxime methiodide (PAM), extrapyramidal manifestations were noticed on hospital day 6. The neurological symptoms worsened, and the diagnosis of parkinsonism was made by a neurologist on hospital day 9. Immediately, biperiden (5mg), an anti-parkinsonism drug, was administered intravenously, and her symptoms markedly improved. "
05/01/2009 - "The CZE measurement opens the way to the fast and reliable determination of pyridinium aldoxime concentrations in serum, cerebrospinal fluid and brain, thereby monitoring blood-brain and blood-CSF penetration of pyridinium aldoxime-type antidotes clinically used in organophosphate poisoning."
01/01/2003 - "The methods of bioinformatics, molecular modelling, and quantitative structure-activity relationships (QSARs) using regression and artificial neural network (ANN) analyses were applied to develop safer aldoxime antidotes against poisoning by organophosphorus (OP) agents with high, mean, and low aging rates. "
09/01/1964 - "[ALPHA-PYRIDYL-ALDOXIME SULFOMETHYLATE (7676 RP) PER OS, IN THE PREVENTION OF ACUTE ORAL POISONING WITH MALATHON]."
11/01/1993 - "Studies on the therapeutic effect of 2-pyridine aldoxime methiodide (2-PAM) in mammals following organophosphorus compound-poisoning (report III): distribution and antidotal effect of 2-PAM in rats."
08/01/1993 - "Studies on the therapeutic effect of 2-pyridine aldoxime methiodide (2-PAM) in mammals following organophosphorus compound (OP)-poisoning (report II): aging of OP-inhibited mammalian cholinesterase."
01/01/1985 - "The present study demonstrates that dose combinations of atropine sulfate and 2-pyridine aldoxime methylchloride (2-PAM), which do not produce any overt toxic effects on the behavior of mice or guinea pigs in a stable environment, elicit clonic-tonic convulsions and death when the animals are physically stressed by cold water swimming. "
01/01/1985 - "Atropine sulfate and 2-pyridine aldoxime methylchloride elicit stress-induced convulsions and lethality in mice and guinea pigs."
01/01/2007 - "In model A, atropine sulfate (2.0 mg/kg i.m.) and pyridine-2-aldoxime methylchloride (2-PAM; 25.0 mg/kg i.m.) were given 1 min after nerve agent challenge, and the tested anticonvulsant was given (i.m.) 5 min after seizure onset. "
|4.||Dehydration (Water Stress)
08/09/2012 - "The enzymatic dehydration of Z-acetaldoxime was explored through QM/MM calculation using two different QM regions and covering all three possible spin states. "
08/08/2003 - "The gene product expressed in Escherichia coli catalyzed the dehydration of aldoxime into nitrile. "
06/01/2000 - "On the other hand, all of 19 nitrile-degrading microorganisms (13 species, 7 genera) were found to exhibit aldoxime dehydration activity. "
06/01/2000 - "All of the active strains exhibited not only the aldoxime-dehydration activity to form nitrile but also nitrile-hydrolyzing activity. "
10/01/2015 - "These materials were active and selective aldoxime dehydration catalysts, and postsynthesis-treated MIL-100 (Fe) produced the desired nitriles with 100 % conversion and selectivities >90 % under mild reaction conditions and in short reaction times. "
04/01/1962 - "Pralidoxime chloride (pyridine-2-aldoxime methochloride; Protopam Chloride) and 1,1'-trimethylenebis(4-hydroxyiminomethylpyridinium bromide) (TMB-4) antagonize the spasm of the isolated or intact small intestine of the rabbit caused by the anticholinesterase, echothiophate iodide (S-2-dimethylaminoethyl OO-diethyl phosphorothiolate methiodide; Phospholine Iodide). "
|4.||pralidoxime (Protopam Chloride)
|8.||Parathion (Ethyl Parathion)
|9.||Hemeproteins (Heme Protein)