brassinolide
14
relevant articles (0 outcomes,
1 trials/studies)
found for this Bio-Agent
Description:
plant growth promoting steroidal lactone from rape pollen; RN given refers to (2alpha,3alpha,5alpha,22R,23R,24S)-isomer; structure in first source
Also Known As:
24-epibrassinolide; 2alpha,3alpha,22alpha,23alpha-tetrahydroxy-24alpha-methyl-B-homo-7-oxa-5alpha-cholestan-6-one; brassinolide, (2alpha,3alpha,5alpha,22S,23S)-isomer; brassinolide, (2alpha,3alpha,5alpha.22R,23R)-isomer; B-Homo-7-oxaergostan-6-one, 2,3,22,23-tetrahydroxy-, (2alpha,3alpha,5alpha,22R,23R,24S)-
Bio-Agent Context: Research Results
Experts
Related Diseases
| 1. | Prostatic Neoplasms (Prostate Cancer)
05/01/2007
- " The present study was carried out to investigate the effect of brassinolide on androgen-independent human prostate cancer PC-3 cell viability" 05/01/2007
- " Brassinolide might therefore be a promising candidate for the treatment of prostate cancer." 05/01/2007
- " Brassinolide, a plant sterol from pollen of Brassica napus L., induces apoptosis in human prostate cancer PC-3 cells." 01/01/2008
- " Therefore, in our next series of experiments, we tested the effects of the most promising and readily available BR analogues with interesting anticancer properties, 28-homocastasterone (1) and 24-epibrassinolide (2), on the viability, proliferation, and cycling of hormone-sensitive/insensitive (MCF-7/MDA-MB-468) breast and (LNCaP/DU-145) prostate cancer cell lines to determine whether the discovered cytotoxic activity of BRs could be, at least partially, related to brassinosteroid-nuclear receptor interactions"
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| 2. | Dwarfism
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| 3. | Heat Stress Disorders (Heat Stress)
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| 4. | Rupture
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| 5. | Neoplasms (Cancer)
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