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pregna-4,17-diene-3,16-dione (guggulsterone)

steroid from guggulu extract; RN & N1 from C1 Form index; RN given refers to cpd without isomeric designation; structure in first source; antagonist of farnesoid X receptor
Also Known As:
guggulsterone; (Z)-guggulsterone; pregna-4,17-diene-3,16-dione, (17E)-isomer; pregna-4,17-diene-3,16-dione, (17Z)-isomer; (17E)-pregna-4,17(20)-diene-3,16-dione
Networked: 62 relevant articles (6 outcomes, 19 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Xiao, Dong: 7 articles (10/2015 - 11/2005)
2. Zeng, Yan: 6 articles (10/2015 - 11/2005)
3. Xu, Hong-Bin: 5 articles (09/2014 - 10/2009)
4. Singh, Shivendra V: 5 articles (03/2011 - 11/2005)
5. Macha, Muzafar A: 4 articles (12/2013 - 01/2010)
6. Li, Ling: 4 articles (10/2013 - 10/2009)
7. Kim, Joo Sung: 4 articles (06/2013 - 12/2006)
8. Kim, Jung Mogg: 4 articles (06/2013 - 12/2006)
9. Jung, Hyun Chae: 4 articles (06/2013 - 12/2006)
10. Aggarwal, Bharat B: 4 articles (11/2008 - 11/2004)

Related Diseases

1. Colitis
2. Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
3. Neoplasms (Cancer)
4. Prostatic Neoplasms (Prostate Cancer)
5. Colonic Neoplasms (Colon Cancer)

Related Drugs and Biologics

1. NF-kappa B (NF-kB)
2. I-kappa B Kinase
3. Doxorubicin (Adriamycin)
4. P-Glycoprotein
5. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
6. Small Interfering RNA (siRNA)
7. Genistein
8. gemcitabine
9. Transcription Factors (Transcription Factor)
10. Thromboplastin (Tissue Factor)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Ayurvedic Medicine (Siddha Medicine)
3. Subcutaneous Injections
4. Drug Therapy (Chemotherapy)