|1.||Silverman, Robert H: 5 articles (06/2014 - 01/2003)|
|2.||Boissinot, Stéphane: 3 articles (09/2015 - 08/2008)|
|3.||De Meirleir, Kenny: 3 articles (11/2005 - 04/2002)|
|4.||Rath, Pramod C: 2 articles (08/2014 - 06/2007)|
|5.||Zhou, Aimin: 2 articles (01/2014 - 01/2003)|
|6.||Dvora, Shira: 2 articles (04/2012 - 08/2008)|
|7.||Ferguson, William: 2 articles (04/2012 - 08/2008)|
|8.||Carr, Daniel J J: 2 articles (04/2007 - 07/2005)|
|9.||Austin, Bobbie Ann: 2 articles (04/2007 - 07/2005)|
|10.||Williams, Bryan R G: 2 articles (04/2007 - 01/2003)|
12/01/2006 - "Deletion of the oligo(A) tract in BMV RNA3 inhibited synthesis of sgRNA3a during infection. "
03/01/1995 - "The 2',5'-oligoadenylate (2-5A) system is involved in the defense of mammalian cells against virus infection. "
02/01/1993 - "The 2',5'-oligoadenylate system (2-5A system) has an essential role in the establishment of the antiviral state of cells exposed to virus infection. "
07/15/1999 - "Since the oligoadenylate/RNase L system provides early protection against virus infection, we hypothesize that M1204 prevents virus-induced cell death in DC."
09/01/2015 - "The oligoadenylate synthetase 1 (OAS1) enzyme acts as an innate sensor of viral infection and plays a major role in the defense against a wide diversity of viruses. "
|2.||Chronic Fatigue Syndrome (Myalgic Encephalomyelitis)
06/01/2005 - "2',5'-Oligoadenylate size is critical to protect RNase L against proteolytic cleavage in chronic fatigue syndrome."
04/01/2002 - "A 2',5'-oligoadenylate (2-5A)-dependent 37-kDa form of RNase L has been reported in extracts of peripheral blood mononuclear cells (PBMC) from individuals with chronic fatigue syndrome (CFS). "
07/01/1997 - "Previous studies from this laboratory have demonstrated a statistically significant dysregulation in several key components of the 2',5'-oligoadenylate (2-5A) synthetase/RNase L and PKR antiviral pathways in chronic fatigue syndrome (CFS) (Suhadolnik et al. Clin Infect Dis 18, S96-104, 1994; Suhadolnik et al. In Vivo 8, 599-604, 1994). "
11/01/2005 - "This paper provides an overview of the evidence addressing the impairments of the 2'-5' oligoadenylate (2-5 A) synthetase/RNase L pathway in Chronic Fatigue Syndrome (CFS) patients. "
06/01/2005 - "A dysregulation in the 2',5'-oligoadenylate (2-5A)-dependent RNase L antiviral pathway has been detected in peripheral blood mononuclear cells (PBMC) of chronic fatigue syndrome (CFS) patients, which is characterized by upregulated 2-5A synthetase and RNase L activities, as well as by the presence of a low molecular weight (LMW) 2-5A-binding protein of 37-kDa related to RNase L. "
|3.||Breast Neoplasms (Breast Cancer)
04/01/1988 - "2', 5' oligo (A) synthetase levels in interferon-sensitive or resistant breast cancer cells."
10/01/1989 - "In the present study the intracellular activity of oligoadenylate synthetase and ribonuclease have been evaluated in two human breast cancer cell lines treated with tamoxifen, a well known antiestrogenic drug. "
11/28/1983 - "Infection of 13 month-old C3H mice with EMC virus or inoculation with the interferon inducer poly(I)poly(C) results in elevated levels of the enzyme 2',5' oligo(A) synthetase only in animals with spontaneous tumors (breast cancer or hepatomas). "
|4.||Virus Diseases (Viral Diseases)
08/01/1990 - "2',5'-Oligoadenylate (2-5A) synthetase is an intracellular enzyme induced during viral diseases and after clinical administration of interferons (IFN). "
04/01/1994 - "In the study presented here, this interferon-induced marker, as well as the 2',5'-oligoadenylate synthetases, was measured in circulating mononuclear cells from 21 patients with acute hepatitis A, 20 patients with acute hepatitis B and 14 patients with acute hepatitis C for determination of the activation of the interferon system in these viral diseases. "
|5.||Liver Cirrhosis (Hepatic Cirrhosis)
11/01/2015 - "The aim of this study was to assess the impact of genetic variants of oligoadenylate synthetase 1 (OAS1) single-nucleotide polymorphism (SNP) rs10774671 at the exon 7 splice acceptor site on liver fibrosis progression and hepatitis C virus (HCV) outcome in Egyptian HCV genotype 4 patients. "
11/01/1999 - "In these patients, serum levels of sIFN alpha/beta receptor were correlated with those of alanine transaminase (ALT) (P <.05), (2'-5')serum oligo(A) synthetase (2-5AS) (P <.0001), and pathological stages of liver fibrosis (P <.01). "
|1.||pppA(2'p5'A)n-dependent ribonuclease (RNase L)
|4.||2',5'-Oligoadenylate Synthetase (2',5' Oligoadenylate Synthetase)
|6.||RNA Splice Sites
|9.||beta 2-Microglobulin (beta 2 Microglobulin)
|10.||Messenger RNA (mRNA)
|1.||Deep Brain Stimulation