3-hydroxypyridine

01/01/2004 - "[Efficacy of derivatives of 3-hydroxypyridine and succinic acid in diabetic patients with the diabetic foot]."

01/01/1987 - "It was found during experiments using three models of hypoxia (hypobaric, normobaric, hemic) in mice that derivatives of 3-hydroxypyridine possess an antihypoxic effect. "
05/01/1987 - "[Protective action of an antioxidant of the 3-hydroxypyridine class on the contractility and electrogenesis of the heart muscle in hypoxia and reoxygenation]."
05/01/1987 - "The effect of SD-6, a 3-hydroxypyridine antioxidant, on the pattern of variation in contraction intensity, contracture and membrane potentials were assessed in experimental studies on isolated left ventricular papillary muscles of rats, exposed to hypoxia and reoxygenation. "
05/01/2010 - "Experiments with occlusion of the common carotid artery in mice demonstrated that, unlike mexidol and SK-170, single injection of new derivatives of 3-hydroxypyridine (3-HP) SK-100 and IBKhF-2, and semax have an anti-hypoxic action on the model of acute normobaric hypoxia with hypercapnia. "
11/01/2007 - "The paper presents the results of experimental and clinical testing of 3-hydroxypyridine derivatives (emoxipin, mexidol and new compounds) various extreme conditions (hypoxia, hyper- and hypothermia, vibration, hypokinesia, ionizing and nonionizing radiation and others). "

07/16/2004 - "Enhancement of UVA-induced intracellular peroxide formation and p38 mitogen-activated protein kinase-dependent stress signaling suggest a photooxidative mechanism of skin cell photosensitization by 3-hydroxypyridine derivatives. "
07/16/2004 - "Photosensitization of cultured human skin keratinocytes (HaCaT) and fibroblasts (CF3) by endogenous and synthetic 3-hydroxypyridine derivatives led to a dose-dependent inhibition of proliferation, cell cycle arrest in G2/M, and induction of apoptosis, all of which were reversible by thiol antioxidant intervention. "
07/16/2004 - "A structure-activity relationship study of skin cell photosensitization by endogenous pyridinium derivatives (pyridinoline, desmosine, pyridoxine, pyridoxamine, pyridoxal, pyridoxal-5'-phosphate) and various synthetic hydroxypyridine isomers identified 3-hydroxypyridine and N-alkyl-3-hydroxypyridinium cation as minimum phototoxic chromophores sufficient to effect skin cell sensitization toward UVB and UVA, respectively. "

05/01/1995 - "Models of neuropathic pain syndrome and adjuvant arthritis were used to study the effect of mexidole, an antioxidant from the 3-hydroxypyridine group. "

02/03/2019 - "The objective of this study is to increase the effectiveness of pharmacological correction of retinal ischemia by using new 3-hydroxypyridine derivative⁻l-isomer of ethylmethylhydroxypyridine malate. "