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N-acetylamrinone

structure given in first source

Also Known As:

N-(1,6-dihydro-5-oxo(3,4'-bipyridin)-5-yl)acetamide; Acetamide, N-(1,6-dihydro-6-oxo(3,4'-bipyridin)-5-yl)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aminopyridines: 77
    - Amrinone: 346
      - N-acetylamrinone: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Aminopyridines: 77
      - Amrinone: 346
        N-acetylamrinone: 2

Related Diseases

1.	Sepsis (Septicemia) 09/01/1996 - "Hemodynamic effects of N-acetylamrinone in a porcine model of group B streptococcal sepsis." 09/01/1996 - "We conclude that amrinone, but not N-acetylamrinone, causes pulmonary vasodilation in a porcine model of sepsis and that the parent drug is the sole active component in amrinone."
2.	Thrombocytopenia (Thrombopenia) 06/01/1993 - "This association suggests that N-acetylamrinone, and not amrinone, may be the mediator of thrombocytopenia in children receiving amrinone." 06/01/1993 - "N-Acetylamrinone peak concentration, steady-state concentration, N-acetylamrinone AUC, and ratio of N-acetylamrinone to amrinone were greater in patients with thrombocytopenia. " 06/01/1993 - "Eighteen children receiving amrinone after heart surgery were prospectively evaluated to correlate the pharmacokinetics of amrinone and N-acetylamrinone with thrombocytopenia. "

Related Drugs and Biologics

1.	Amrinone (Amrinon)