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piperidine-4-sulfonic acid

specific GABA agonist

Also Known As:

piperidine-4-sulphonic acid; 4-Piperidinesulfonic acid

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - piperidine-4-sulfonic acid: 3

Related Diseases

1.

Seizures (Absence Seizure)

02/05/1990 - "Injections of the GABAA-agonist piperidine-4-sulfonic acid and the GABAB-agonist (-)baclofen in the CeM markedly facilitated myoclonic and clonic seizures, but had different effects on tonic seizures. "
01/01/1991 - "Injections of both the GABAA agonist piperidine-4-sulfonic acid and the GABAB agonist (-)baclofen in the laterodorsal tegmental nucleus produced a dose-dependent suppression of behavioral arousal and a reduction in the threshold of myoclonic and clonic but not tonic seizures induced by bicuculline and pentylenetetrazol. "
07/01/1990 - "Injections of the direct selective GABAA agonist, piperidine-4-sulfonic acid or the indirect GABAA agonists, flurazepam and pentobarbital, in this region depressed arousal and facilitated myoclonic and clonic seizures induced by pentylenetetrazol but only caused slight inhibition of tonic seizures. "

Related Drugs and Biologics

1.	Pentylenetetrazole (Metrazol)
2.	Baclofen
3.	Pentobarbital (Nembutal)
4.	Flurazepam (Dalmane)
5.	Bicuculline

Related Therapies and Procedures

1.	Injections