closantel

01/15/2015 - "Finally, we evaluated the use of closantel (Flukiver(®), Elanco Animal Health, subcutaneous administration at 10mg/kg) to treat rumen fluke infection on 3 herds, but no significant reduction in egg output post-treatment was found. "
01/01/1985 - "Closantel remained effective for 2 months in preventing infections of G intestinalis larvae in these foals and yearlings. "
08/01/2006 - "Treatment of infected cells 1 day post infection with closantel cleared infection in dose-dependent manner. "
12/01/1985 - "The efficacy of closantel against experimentally induced Fascioloides magna infection in sheep was studied. "
04/01/1985 - "Study of the mode of action of the anti-parasitic 'hydrogenophore', closantel, revealed that mitochondria isolated from livers of untreated rats, 13 weeks after infection with Fasciola hepatica metacercariae, were uncoupled. "

02/01/1993 - "Closantel at the rate of 10 mg/kg body weight was 100% effective against the 2 resistant strains of the parasite as indicated by faecal egg count and worm reduction. "
12/01/2015 - "On each farm, 10 F. hepatica coproantigen-positive and F. hepatica egg-positive animals were allocated after 12-16 weeks of housing into groups and treated topically with a minimum of 20 mg closantel per kg body weight. "
08/01/1999 - "The closantel-treated group gained more body weight but the first six-monthly greasy fleece yield was greater in the group treated with medicated pellets. "
10/25/1996 - "The goats were administered closantel once orally at a dose of 10 mg/kg body weight. "
12/01/1985 - "In the 1st experiment, closantel was given orally to 5 groups of 6 sheep each at dosages of 0 (nontreated control), 5, 7.5, 10, and 15 mg/kg of body weight. "

12/01/2019 - "In addition, closantel (a WNK1-SPAK/OSR1 inhibitor) improved pain behaviors, downregulated SPAK/OSR1 and NKCC1 expression, and upregulated KCC2 expression in BCP rats. "

05/08/2015 - "The anthelmintic closantel has shown promise in abrogating the L3 molting of Onchocerca volvulus, the causative agent of the infectious disease onchocerciasis. "

05/08/2015 - "The anthelmintic closantel has shown promise in abrogating the L3 molting of Onchocerca volvulus, the causative agent of the infectious disease onchocerciasis. "