|1.||Cheung, Nai-Kong V: 5 articles (02/2010 - 06/2002)|
|2.||Cheung, Irene Y: 5 articles (02/2010 - 06/2002)|
|3.||Furukawa, Koichi: 4 articles (03/2014 - 01/2003)|
|4.||Furukawa, Keiko: 4 articles (03/2014 - 01/2003)|
|5.||Biswas, Kaushik: 3 articles (01/2015 - 05/2007)|
|6.||Lo Piccolo, M Serena: 3 articles (10/2003 - 06/2002)|
|7.||Kushner, Brian H: 3 articles (10/2003 - 06/2002)|
|8.||Laurent, Viviana E: 2 articles (09/2013 - 03/2010)|
|9.||Chantada, Guillermo L: 2 articles (09/2013 - 03/2010)|
|10.||Alonso, Daniel F: 2 articles (09/2013 - 03/2010)|
08/15/2001 - "The current study found that molecular detection of GD2 synthase transcript in NB BMs may have potential value in detecting rare tumor cells."
01/01/2015 - "TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells."
03/01/2010 - "We also confirmed the expression of GD2 synthase by RT-PCR and immunohistochemical detection of the ganglioside in human RB tumors xenotransplanted in nude mice. "
02/01/2010 - "6/10 (60%) tumor tissues or BM samples were positive (median 332.7 units; range 13-2323 units); 8/19 (42%) untreated patients were GD2/GM2 synthase positive in their PB prior to beginning therapy (median 10.2; range 5.1-32.2); 3/4 (75%) patients who were first tested when they developed recurrent disease were positive in their PB (median 16.1; range 8.5-19.9). "
02/01/2010 - "GD2/GM2 synthase transcript levels were obtained from tumor tissue, BM, or PB of 29 patients in the pilot study. "
11/20/2008 - "PHOX2B is superior to TH and GD2 synthase in specificity and sensitivity for MRD detection of neuroblastoma by using real-time quantitative PCR. "
09/24/2002 - "F-11A cells are a substrain of murine neuroblastoma F-11 cells that contain only low endogenous ST2 and GalNAcT activity. "
08/15/2001 - "GD2 synthase: a new molecular marker for detecting neuroblastoma."
10/15/1992 - "Thus, the high GD2:GD3 ratios characteristic of most neuroblastomas result from low levels of GD3 synthase as well as high levels of GD2 synthase. "
03/01/2010 - "The GD2 ganglioside is known to be expressed by RB cells that metastasize in bone marrow, and the activity of the enzyme responsible for its synthesis, GD2 synthase, can be detected in neuroblastoma, which shares many phenotypic features with RB. "
|3.||Melanoma (Melanoma, Malignant)
03/07/2014 - "Quantitative RT-PCR revealed that melanomas expressed high levels of mRNA of GD3 synthase and GM2/GD2 synthase genes and low levels of GM1/GD1b synthase genes compared with melanocytes. "
10/03/1997 - "Introduction of the cDNA clone into a mouse melanoma line B16 previously transfected with a GM2/GD2 synthase gene resulted in the neo-synthesis of GM1. "
10/20/1995 - "267, 12082-12089) had isolated a putative cDNA coding for beta 1,4 N-acetylgalactosaminyltransferase (GM2/GD2 synthase) and demonstrated the presence of GM2 and/or GD2 gangliosides in melanoma cell lines stably transfected with this gene. "
10/20/1995 - "Analysis of melanoma cells stably transfected with beta 1,4GalNAc transferase (GM2/GD2 synthase) cDNA: relative glycosyltransferase levels play a dominant role in determining ganglioside expression."
07/15/2007 - "Blood samples from 90 women with the American Joint Committee on Cancer stages I to III breast cancer and 39 age-matched normal healthy volunteers were assessed by qRT for mRNA expression of three markers: stanniocalcin-1 (STC-1), N-acetylgalactosaminyltransferase (GalNacT), and melanoma antigen gene family-A3 (MAGE-A3). "
|4.||Retinoblastoma (Glioblastoma, Retinal)
|5.||Neoplasm Metastasis (Metastasis)
01/10/2003 - "Suppression of lung metastasis of mouse Lewis lung cancer P29 with transfection of the ganglioside GM2/GD2 synthase gene."
01/10/2003 - "Ganglioside functions in tumor metastasis were analyzed by carbohydrate remodeling of a mouse Lewis lung cancer (subline P29) by introducing beta1,4GalNAc-T cDNA. "
06/11/2003 - "According to our restricted analysis of only those 39 glycosyltransferases present on the GeneChip U95A, alterations of sialyltransferases ST6Gal-I, ST3Gal-IV, of fucosyltransferases FT-VI, FT-III, and probably FT-VIII, of GalNacT-I, and of beta4GalT-II seem to be of relevance for the aberrant biosynthesis of membrane-bound carbohydrates during colonic carcinogenesis and metastasis."
|1.||Messenger RNA (mRNA)
|2.||RNA-Directed DNA Polymerase (Reverse Transcriptase)
|3.||Complementary DNA (cDNA)
|6.||Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)
|7.||Uridine Diphosphate (UDP)
|9.||Kv Channel-Interacting Proteins (Calsenilin)
|2.||Bone Marrow Purging