|1.||Jayasinghe, Caren: 2 articles (04/2009 - 01/2009)|
|2.||Simiantonaki, Nektaria: 2 articles (04/2009 - 01/2009)|
|3.||Michel-Schmidt, Romi: 2 articles (04/2009 - 01/2009)|
|4.||Kirkpatrick, Charles James: 2 articles (04/2009 - 01/2009)|
|5.||Suburo, Angela M: 2 articles (04/2008 - 11/2002)|
|6.||Dodds, Ricardo A: 2 articles (04/2008 - 11/2002)|
|7.||Xu, Xun: 2 articles (11/2006 - 09/2004)|
|8.||Zhang, Xi: 2 articles (03/2005 - 09/2004)|
|9.||Kuriyama, H: 2 articles (03/2001 - 11/2000)|
|10.||Kuriyama, N: 2 articles (03/2001 - 11/2000)|
11/01/2002 - "It can be concluded that dispase induced a proliferative vitreoretinopathy-like condition in mice, with a strong contribution of macrophage- and glial-derived cells."
11/01/2002 - "A proliferative vitreoretinopathy-like condition induced by intravitreal dispase injection in C57BL/6J mice was studied using ophthalmoscopic and histochemical procedures. "
11/01/2002 - "A mouse model of proliferative vitreoretinopathy induced by dispase."
10/01/2002 - "The ability of intravitreous injection of this ribozyme to prevent or inhibit development of proliferative vitreoretinopathy (PVR) was tested in a dispase-induced rabbit PVR model. "
01/01/2006 - "Experimental model for proliferative vitreoretinopathy by intravitreal dispase: limited by zonulolysis and cataract."
|2.||Vitreous Detachment (Posterior Vitreous Detachment)
01/01/1998 - "To induce a posterior vitreous detachment (PVD) in porcine and human cadaver eyes in vitro with Dispase (Gibco, Grand Island, NY). "
01/01/1998 - "Posterior vitreous detachment with dispase."
11/01/2006 - "To explore the efficacy and safety of dispase on the production of posterior vitreous detachment (PVD) following intravitreal injection at various concentrations for different exposure times in the rabbit eyes. "
01/01/2001 - "To evaluate the role of intravitreal dispase in conjunction with pars plana vitrectomy to facilitate the creation of a posterior vitreous detachment (PVD) in young pig eyes. "
01/01/2001 - "Dispase facilitates posterior vitreous detachment during vitrectomy in young pigs."
09/01/2004 - "Light microscopy showed inflammation in both dispase- and plasmin-treated eyes of groups 5 and 6. However, whereas in plasmin-treated eyes the ERG and cell ultrastructure showed no significant changes, in dispase-treated eyes, the amplitudes of ERG showed a significant reduction from baseline and ultrastructural damage to the retina was detected by transmission electron microscopy. "
11/01/2006 - "Intraocular toxicity including inflammation in anterior chamber, vitreous haze, epiretinal membrane, and retinal damage were found in the experimental eyes with relatively higher concentrations of dispase. "
12/01/1990 - "Propagation in culture of cells obtained by dispase treatment of the excised tumors, followed by selection for drug resistance, revealed that only a fraction of the tumors (27% and 60% for BR-3 and OB-1, respectively) resulted from the growth of the injected cells. "
01/01/1989 - "Neoplastic ECs were obtained after enzymatic digestion of the tumor tissue with dispase. "
01/01/1985 - "Tumor-associated lymphoid cells (TAL) were obtained from tumor tissues by mechanical treatment (NDi fraction) and by enzymatic treatment with Dispase I, a proteolytic enzyme (Di fraction), followed by passage through glass wool columns to deplete tumor cells. "
05/01/1980 - "Use of bacterial neutral protease for disaggregation of mouse tumours and multicellular tumor spheroids."
09/01/1981 - "We used a bacterial neutral protease to disperse KHT solid tumors into single cell suspensions suitable for routine cell kinetic analysis by flow cytometry and for clonogenic cell survival. "
|5.||Wounds and Injuries (Trauma)
01/01/1988 - "Experimental study of treatment of high-velocity projectile wounds with bacterial neutral protease."
07/01/1999 - "Detachment by a short dispase-treatment appeared in our hands the only method for successful and complete epithelial regeneration in full-thickness wounds."
07/01/1999 - "When grafted onto full-thickness skin wounds in pigs, the take of cell sheets detached from the filter with dispase was significantly higher (about 70%) in comparison to mechanically detached keratinocytes (about 15%). "
03/01/1992 - "Following isolation of the mesenchyme and epidermis by treatment with Dispase and separate culturing, the capacity for wound closure in vitro was found to be retained only by the mesenchyme. "
06/01/1991 - "In order to look for the best conditions required for the utilization of cultured epithelium in the treatment of burn wounds, some experiments have been performed studying the storage of dispase-detached cultures. "
|6.||Ovarian epithelial cancer
|9.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|10.||Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)
|1.||Drug Therapy (Chemotherapy)
|3.||Heterologous Transplantation (Xenotransplantation)