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dihydroneopterin triphosphate pyrophosphohydrolase
human liver enzyme removes triphosphate to give 6-pyruvoyl-tetrahydrobiopterin
Also Known As:
7,8-dihydroneopterin triphosphate phosphate eliminating enzyme; phosphate eliminating enzyme
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Enzymes and Coenzymes: 1
Enzymes: 152586
Hydrolases: 2166
Acid Anhydride Hydrolases
Pyrophosphatases: 171
dihydroneopterin triphosphate pyrophosphohydrolase: 2
Related Diseases
1.
Phenylketonurias (Phenylketonuria)
05/01/1985 - "
Atypical phenylketonuria with "dihydrobiopterin synthetase" deficiency: absence of phosphate-eliminating enzyme activity demonstrated in liver.
"
2.
6-pyruvoyl-tetrahydropterin synthase deficiency
05/01/1987 - "
From measurements of the activity of erythrocyte 6-pyruvoyl tetrahydropterin synthase (PTS, formerly called phosphate-eliminating enzyme) and phenylalanine loading tests in the patients and their parents, one patient was demonstrated to be heterozygous for PTS deficiency.
"
Related Drugs and Biologics
1.
Phenylalanine (L-Phenylalanine)
2.
7,8-dihydrobiopterin synthetase
3.
tetrahydropterin