|1.||Hayflick, Susan J: 7 articles (08/2014 - 01/2003)|
|2.||Jackowski, Suzanne: 4 articles (01/2015 - 03/2005)|
|3.||Westaway, Shawn K: 4 articles (07/2005 - 01/2003)|
|4.||Leonardi, Roberta: 3 articles (01/2015 - 03/2005)|
|5.||Hayflick, S J: 3 articles (06/2007 - 08/2001)|
|6.||Gitschier, J: 3 articles (06/2007 - 08/2001)|
|7.||Zhang, Yong-Mei: 3 articles (01/2007 - 03/2005)|
|8.||Rock, Charles O: 3 articles (01/2007 - 03/2005)|
|9.||Gitschier, Jane: 3 articles (01/2005 - 01/2003)|
|10.||Finazzi, Dario: 2 articles (01/2016 - 08/2010)|
|1.||Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease)
04/01/2005 - "To study pantothenate kinase 2 (PANK2) gene mutations in Chinese patients with Hallervorden-Spatz syndrome (HSS). "
11/01/2013 - "The patient was found to have two mutations in the pantothenate kinase 2 (PANK2) gene that have been previously associated with pantothenate kinase-associated neurodegeneration: a paternally inherited p.G521R and maternally inherited p.T528M. "
12/22/2009 - "To investigate the clinical features and detection of pantothenate kinase 2 (PANK2) gene mutation in a Chinese patient with Hallervorden-Spatz syndrome (HSS). "
12/22/2009 - "[Clinical manifestations and detection of pantothenate kinase 2 gene mutation in a patient with Hallervorden-Spatz syndrome]."
10/01/2009 - "Pantothenate-Kinase-Associated-Neurodegeneration (PKAN) is a devastating disease, resulting from mutations in pantothenate kinase 2 (PANK2), one of the four human pantothenate kinase genes (PANK1-4). "
07/09/2010 - "tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations."
04/01/2009 - "tuberculosis pantothenate kinase are remarkable and novel."
06/21/2013 - "Pantothenate kinase, a key enzyme in the universal biosynthesis of the essential cofactor CoA, was targeted in this study to find new tuberculosis drugs. "
05/01/1967 - "Pantothenic acid metabolism during avian malaria infection: pantothenate kinase activity in duck erythrocytes and in Plasmodium lophurae."
04/24/1998 - "These results contrast with those of previous studies in which it was proposed that the avian malaria parasite Plasmodium lophurae lacks pantothenate kinase (as well as the other enzymes for the synthesis of coenzyme A) and is reliant upon the uptake of preformed coenzyme A from the host cell cytosol."
|4.||Neurodegenerative Diseases (Neurodegenerative Disease)
02/01/2009 - "Low-frequency rTMS of the premotor cortex reduces complex movement patterns in a patient with pantothenate kinase-associated neurodegenerative disease (PKAN)."
01/30/2007 - "The human isoform 2 of pantothenate kinase (PanK2) is localized to the mitochondria, and mutations in this protein are associated with a progressive neurodegenerative disorder. "
06/01/2012 - "Pantothenate kinase-associated neurodegeneration (PKAN) is a neurodegenerative disorder caused by pantothenate kinase (PANK2) gene mutations. "
04/13/2010 - "Pantothenate kinase-associated neurodegeneration (PKAN), a progressive neurodegenerative disorder, is associated with impairment of pantothenate kinase function. "
03/01/2004 - "Patients with Hallervorden-Spatz syndrome, an autosomal recessive, progressive neurodegenerative disorder, have mutations in a novel pantothenate kinase gene (PANK2). "
|5.||Dystonia (Limb Dystonia)
01/01/2015 - "The patient, initially suspected of idiopathic isolated dystonia, finally presented with pantothenate kinase 2-associated neurodegeneration phenotype and was a carrier of two PANK2 mutations. "
12/01/2003 - "Disease caused by mutations in the gene encoding pantothenate kinase 2 (PANK2) is characterized by dystonia and pigmentary retinopathy in children or speech and neuropsychiatric defects in adults, in concert with a specific pattern on MRI of the brain. "
02/01/2009 - "Pantothenate kinase-associated neurodegenerative disease (PKAN) is a secondary generalized dystonia associated with an accumulation of iron in the basal ganglia and increased motor cortex excitability. "
10/23/2006 - "Mutations in the pantothenate kinase 2 gene (PANK2) are the cause of pantothenate kinase associated neurodegeneration (PKAN), an autosomal recessive (AR) disorder characterized by motor symptoms as such as dystonia or parkinsonism, mental retardation, retinitis pigmentosa and iron accumulation in the brain. "
11/01/2010 - "We cover dopa-responsive dystonia, Wilson's disease, Parkin-, PINK1-, and DJ-1-associated parkinsonism (PARK2, 6, and 7), x-linked dystonia-parkinsonism/Lubag (DYT3), rapid-onset dystonia-parkinsonism (DYT12) and DYT16 dystonia, the syndromes of Neurodegeneration with Brain Iron Accumulation (NBIA) including pantothenate kinase (PANK2)- and PLA2G6 (PARK14)-associated neurodegeneration, neuroferritinopathy, Kufor-Rakeb disease (PARK9) and the recently described SENDA syndrome; FBXO7-associated neurodegeneration (PARK15), autosomal-recessive spastic paraplegia with a thin corpus callosum (SPG11), and dystonia parkinsonism due to mutations in the SLC6A3 gene encoding the dopamine transporter. "
|1.||Coenzyme A (CoA)
|4.||Neurodegeneration with brain iron accumulation (NBIA)
|5.||Pantothenic Acid (Calcium Pantothenate)
|6.||Phospholipases A2 (Phospholipase A2)
|7.||Protein Isoforms (Isoforms)
|9.||Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)
|1.||Deep Brain Stimulation