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N-acetylglucosamine deacetylase

Also Known As:

N-acetyl-D-glucosaminyl N-deacetylase; glucosaminyl N-deacetylase; glucosaminyl deacetylase

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Amidohydrolases: 43
      - N-acetylglucosamine deacetylase: 6

Experts

1.	Holl, Ralph: 1 article (02/2014)
2.	Jose, Joachim: 1 article (02/2014)
3.	Löppenberg, Marius: 1 article (02/2014)
4.	Melesina, Jelena: 1 article (02/2014)
5.	Sippl, Wolfgang: 1 article (02/2014)
6.	Szermerski, Marina: 1 article (02/2014)
7.	Wichapong, Kanin: 1 article (02/2014)

Related Diseases

1.	Mastocytoma 04/23/1996 - "Expression of the mouse mastocytoma glucosaminyl N-deacetylase/ N-sulfotransferase in human kidney 293 cells results in increased N-sulfation of heparan sulfate." 04/08/1994 - "A 110-kDa protein involved in heparin biosynthesis in mouse mastocytoma cells was previously shown to express both glucosaminyl N-deacetylase and N-sulfotransferase activity. " 04/08/1994 - "cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin."
2.	Diabetic Nephropathies (Diabetic Nephropathy) 06/01/1993 - "Impaired heparan sulphate biosynthesis through diabetes-induced inhibition of glucosaminyl N-deacetylase may have a central role in the development of diabetic nephropathy, and genetic differences in the vulnerability of the N-deacetylase could influence the risk of developing nephropathy. " 06/01/1993 - "Glucosaminyl N-deacetylase in cultured fibroblasts; comparison of patients with and without diabetic nephropathy, and identification of a possible mechanism for diabetes-induced N-deacetylase inhibition." 04/01/1992 - "It is concluded that the diabetes induced inhibition of glucosaminyl N-deacetylase may play an important role in the pathogenesis of diabetic nephropathy."
3.	Infections 02/01/2014 - "The inhibition of the UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase (LpxC) represents a promising strategy to combat infections caused by multidrug-resistant Gram-negative bacteria. "
4.	Diabetic Angiopathies (Diabetic Angiopathy) 04/01/1993 - "Inhibition of glucosaminyl N-deacetylase activity, a key enzyme in heparan sulphate sulphation, may be involved in the development of late diabetic vascular complications. "
5.	Diabetes Mellitus 04/01/1993 - "Diabetes mellitus induced inhibition of glucosaminyl N-deacetylase: effect of short-term blood glucose control in diabetic rats."

Related Drugs and Biologics

1.	Sulfotransferases
2.	Enzymes
3.	Complementary DNA (cDNA)
4.	Uridine Diphosphate (UDP)
5.	Proteins (Proteins, Gene)
6.	Heparitin Sulfate (Heparan Sulfate)
7.	Heparin (Liquaemin)

Related Therapies and Procedures

1.	Glycemic Control