|1.||Gey, Laura: 1 article (05/2015)|
|2.||Handreck, Annelie: 1 article (05/2015)|
|3.||Mall, Eva Maria: 1 article (05/2015)|
|4.||Elger, Deborah Annina: 1 article (05/2015)|
|5.||Gernert, Manuela: 1 article (05/2015)|
|6.||Gelderblom, Hans: 1 article (12/2013)|
|7.||Rosing, Hilde: 1 article (12/2013)|
|8.||van Warmerdam, Laurence J C: 1 article (12/2013)|
|9.||Beijnen, Jos H: 1 article (12/2013)|
|10.||Slingerland, Marije: 1 article (12/2013)|
03/01/2013 - "Hypersensitivity reaction studies of a polyethoxylated castor oil-free, liposome-based alternative paclitaxel formulation."
03/01/2013 - "The commercial drug paclitaxel (Taxol) may introduce hypersensitivity reactions associated with the polyethoxylated castor oil-ethanol solvent. "
04/01/1994 - "Since the concentration and total amount of Cremophor EL (polyoxyethylene castor oil), which is suspected to be a causative agent for high incidence rate of hypersensitivity reactions by clinical formulation of paclitaxel, inevitably decrease in such a low dose setting, these results should be taken into considerations when exploring the optimal schedule of paclitaxel clinically."
10/01/1995 - "Because of its low aqueous solubility, paclitaxel is administered in polyethoxylated castor oil (Cremophor EL) and ethanol, a vehicle associated with severe hypersensitivity reactions. "
09/01/1986 - "B30-MDP was found to potently stimulate both humoral and cellular immune responses, the latter by induction of delayed-type hypersensitivity, irrespective of the administration vehicle examined (liposomes, a squalene in water emulsion, Intralipid, phosphate-buffered saline, and Nikkol HCO-60 glucose solution), although the minimum effective dose was dependent on the vehicle used. "
|2.||Anaphylaxis (Anaphylactic Shock)
10/01/2002 - "The anaphylaxis is thought to be attributable to the solubilizing vehicle, polyethoxylated castor oil (Cremophor EL, BASF AG, Ludwingshafen, Germany). "
09/01/2001 - "Intravenous administration of cyclosporine, which contains Cremophor EL (a polyethoxylated castor oil; BASF, Berlin, Germany), has occasionally resulted in an anaphylactic reaction. "
12/01/2010 - "Due to its high lipophilicity, paclitaxel is difficult to administer and requires solubilization with Cremophor EL (polyethoxylated castor oil) and ethanol, which often lead to adverse side effects, including life-threatening anaphylaxis. "
05/01/2015 - "We therefore comprehensively investigated the effects of acute versus chronic treatment using different dosages (5mg/kg, 10mg/kg), application routes (i.p., s.c.), and preparations of CsA (pure substance solved in polyethoxylated castor oil and a ready-to-use drug additionally containing ethanol) on acute seizure thresholds in rats in the pentylenetetrazole seizure threshold test and verified the most harmless protocol in the chronic amygdala-kindling model for temporal lobe epilepsy. "
|4.||Ethanol (Ethyl Alcohol)