4,5-dihydroxy-4,5-dihydrobenzo(e)pyrene

RN given refers to cpd without isomeric designation; structure

Also Known As:

4,5-dihydroxy-4,5-dihydrobenzo(e)pyrene, (cis)-isomer; 4,5-dihydroxy-4,5-dihydrobenzo(e)pyrene, (trans)-isomer; benzo(e)pyrene-trans-4,5-dihydrodiol; trans-4,5-dihydro-4,5-dihydroxybenzo(e)pyrene; trans-4,5-dihydroxy-4,5-dihydrobenzo(e)pyrene

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Papilloma (Papillomatosis) 02/01/1980 - "Control mice and mice treated with 6.0 mumol of benzo(e)pyrene, trans-4,5-dihydroxy-4,5-dihydrobenzo(e)pyrene, trans 9,10-dihydroxy-9,10-dihydrobenzo(e)pyrene, and trans-9,10-dihydroxy-9,10,11,12-tetrahydrobenzo(e)pyrene had a tumor incidence of less than 20% and had less than or equal to 0.25 papillomas/mouse. "
2.	Neoplasms (Cancer) 02/01/1980 - "Control mice and mice treated with 6.0 mumol of benzo(e)pyrene, trans-4,5-dihydroxy-4,5-dihydrobenzo(e)pyrene, trans 9,10-dihydroxy-9,10-dihydrobenzo(e)pyrene, and trans-9,10-dihydroxy-9,10,11,12-tetrahydrobenzo(e)pyrene had a tumor incidence of less than 20% and had less than or equal to 0.25 papillomas/mouse. " 02/01/1980 - "Benzo(e)pyrene, trans-4,5-dihydroxy-4,5-dihydrobenzo(e)pyrene, and trans-9,10-dihydroxy-9,10-dihydrobenzo(e)pyrene had little or no tumorigenic activity in lung tissue, although trans-9,10-dihydroxy-9,10-dihydrobenzo(e) pyrene did induce a significant number of hepatic tumors. "

Related Drugs and Biologics

1.	pyrene
2.	benzo(e)pyrene
3.	9,10- dihydroxy- 9,10- dihydrobenzo(e)pyrene