H antigen

03/01/1983 - "The accumulation of type 2 chain H-antigen in oral premalignant lesions may prove helpful in early diagnosis of epithelial cancer."
08/15/1986 - "Previous studies indicated that BCL1 tumor immunity in C.B-20 mice was associated with a T cell-mediated immune response against H-40, a minor histocompatibility (H) antigen controlled by a gene linked to the Igh locus. "
09/01/1985 - "A study was undertaken to obtain baseline information for future studies of H-antigen expression in urothelial tumors. "
12/20/2006 - "Input of the minor H antigen typing results subsequently provides all relevant information for a given patient/donor pair and additional information on the putative graft-versus-host, graft-versus-tumor and host-versus-graft reactivities. "
09/01/1999 - "Tumors that expressed H antigen and high levels of Le(y) (> 50%) had a poor prognosis (P = .0006 and P = .0056, respectively). "

06/01/2013 - "This study included 80 children suffering from typhoid fever, among which 40 were confirmed by blood culture isolation and 40 had possible typhoid fever based on high Widal's titre (a four-fold rise in the titre of antibody to typhi "O" and "H" antigen was considered as a positive Widal's test result). "
11/01/2001 - "PGFRP elicited an increase in antibody titer to typhoid-H antigen. "
10/01/1988 - "typhi) isolated from blood of patients in Japan who had visited Indonesia and returned before the onset of typhoid fever were found to possess the H-antigen Z66 reported by Guinée et al. (1981) but had the naturally occurring H-antigen d. "
09/01/1980 - "[Ionizing radiation-induced changes in the H antigen content of typhoid fever bacteria]."
01/01/1974 - "[The role of H-antigen in postvaccinal immunity against typhoid and paratyphoid]."

05/01/2001 - "Protective efficacy of H antigen from Histoplasma capsulatum in a murine model of pulmonary histoplasmosis."
04/01/2003 - "We developed a seminested PCR for the diagnosis of histoplasmosis that amplifies a portion of the Histoplasma capsulatum H antigen gene. "
05/01/2001 - "Here, we investigated the utility of H antigen to protect mice in a model of pulmonary histoplasmosis. "
12/01/1988 - "Histoplasma capsulatum contains multiple antigens, among them the H antigen and M antigen, which are useful in serologic testing for histoplasmosis. "
05/01/1974 - "In agar gel double-diffusion and complement fixation tests with sera from patients with proven cases of histoplasmosis, blastomycosis, or coccidioidomycosis, these two fractions of H antigen and the one of M antigen reacted only with sera from proven or suspect cases of histoplasmosis and showed reactivity with those sera known to contain only the anti-H or anti-M antibody, respectively. "

01/01/2020 - "However, in some cases the minor H antigen-specific T cells delivered with the graft may be quantitatively insufficient or become functionally impaired over time, leading to leukemia relapse. "
04/30/2009 - "These results provide insight into the control of minor H antigen-specific CD8 T-cell responses, to maximize the graft-versus-leukemia response."
11/27/2008 - "Primary fibroblasts can be efficiently used as allogeneic nonhematopoietic APC for selective depletion of donor T cells reactive to HLA and ubiquitously expressed minor-H antigen disparities in leukemia-stimulated CD8 T-cell lines. "
02/15/2005 - "Since maternal cells traffic into the fetus during pregnancy, we questioned whether cord blood has the potential to generate cytotoxic T cells specific for the hematopoietic minor histocompatibility (H) antigen HA-1 that would support the graft-versus-leukemia effect. "
04/15/1998 - "Resistance of LE750 leukemic cells to induction of the GVL effect could not be attributed to either less sensitivity to lysis by minor H antigen-specific, cytotoxic T cells or to an immunosuppressive activity of LE750 leukemic cells in leukemia-bearing host, when compared with the case of the sensitive leukemia (8313). "

02/01/2011 - "Vaccine-mediated T cell priming was also preserved in the case of multiple minor H antigen disparities, prone to graft-versus-host disease. "
07/01/1998 - "Administration of IL-11 prevented lethal graft-versus-host disease (GVHD) in a murine bone marrow transplant (BMT) model (B6 --> B6D2F1) across MHC and minor H antigen barriers (survival at day 50: 90 vs 20%, P < 0.001). "
08/01/2013 - "The effect of minor H antigen mismatching on the occurrence of graft-versus-host disease (GvHD) and graft-versus-leukemia (GvL) after HLA-matched hematopoietic stem cell transplantation (HSCT) has mainly been demonstrated in single-center studies. "
11/01/2005 - "Despite ubiquitous expression of H7(a), dissemination of a few H7(a)-specific T cells in extralymphoid organs caused neither graft-versus-host disease (GVHD) nor vitiligo because host nonhematopoietic cells were protected by their low expression of MHC class I. Our preclinical model yields unique insights into how minor H antigen-based immunotherapy could be used to treat human solid tumors."