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spleen exonuclease

Also Known As:

3'-exonuclease; 3-exonuclease; phosphodiesterase II; spleen phosphodiesterase

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Exonucleases: 476
        spleen exonuclease: 6

Experts

1.	Beliakova, N V: 1 article (09/2007)
2.	Kravetskaia, T P: 1 article (09/2007)
3.	Krutiakov, V M: 1 article (09/2007)
4.	Legina, O K: 1 article (09/2007)
5.	Ronzhina, N L: 1 article (09/2007)
6.	Shevelev, I V: 1 article (09/2007)

Related Diseases

1.	Ascites 08/01/1972 - "A surface 3'-exonuclease of Novikoff hepatoma ascites cells." 10/01/1973 - "Partial digestion with 3'-exonuclease from ascites cell nuclei established that the 28S RNA region is located at the 5'-end of the 45S precursor. "
2.	Carcinogenesis 09/01/2007 - "The complex of DNA polymerase beta with 3'-exonuclease was shown to be 30 times more accurate than the monomeric polymerase, which can decrease the probability of repair mutagenesis and carcinogenesis."
3.	Mastocytoma 06/25/1983 - "Comparison of the sensitivity of DNA isolated from untreated and mAMSA-treated PY815 mouse mastocytoma cells to hydrolysis by E.coli 3'-exonuclease III and phage lambda or phage T7 5'-exonucleases show that the fragments of chromosomal DNA produced by mAMSA treatment have free 3'-OH termini and blocked 5'-termini."
4.	Radiation Injuries (Radiation Sickness) 05/01/1985 - "In the early period of acute radiation injury both phosphodiesterase I sensitivity to calmodulin and phosphodiesterase II special activity under hydrolysis of 3', 5'-GMP decrease but phosphodiesterase I special activity under hydrolysis of 3', 5'-GMP increases. "
5.	Neuroblastoma 01/01/1996 - "Role of phosphodiesterase II in cross talk between cGMP and cAMP in human neuroblastoma NB-OK-1 cells."

Related Drugs and Biologics

1.	Phosphodiesterase I (5' Exonuclease)
2.	DNA Polymerase beta (DNA Polymerase IV)
3.	RNA (Ribonucleic Acid)
4.	Guanosine Monophosphate (5' Guanylic Acid)
5.	DNA (Deoxyribonucleic Acid)
6.	Calmodulin (Calcium-Dependent Activator Protein)