serine-pyruvate aminotransferase

do not confuse with alanine-glyoxylate aminotransferase (EC 2.6.1.44), even though they may be products of the same gene; index whichever is discussed or both

Also Known As:

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ji, Juling: 1 article (11/2019)
2.	Li, Wenchao: 1 article (11/2019)
3.	Lu, Bing: 1 article (11/2019)
4.	Lu, Peng: 1 article (11/2019)
5.	Shen, Shiqi: 1 article (11/2019)
6.	Shen, Yi: 1 article (11/2019)
7.	Sun, Yufeng: 1 article (11/2019)
8.	Yang, Xuejing: 1 article (11/2019)
9.	Zhang, Xiaojing: 1 article (11/2019)
10.	Chen, Weijian: 1 article (01/2019)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 11/26/2019 - "Loss of alanine-glyoxylate and serine-pyruvate aminotransferase expression accelerated the progression of hepatocellular carcinoma and predicted poor prognosis." 01/15/1986 - "Serine hydroxymethyltransferase activity was present in hepatomas, whereas other enzymes of serine utilization (serine dehydratase and serine aminotransferase) were absent. "
2.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2023 - "The siRNA-mediated knockdown of LCMT1 inhibited glycolysis, promoted mitochondrial dysfunction, and increased intracellular pyruvate levels by upregulating the expression of alani-neglyoxylate and serine-pyruvate aminotransferase (AGXT). "
3.	Sarcoma (Soft Tissue Sarcoma) 01/01/1988 - "The activities of 3-phosphoglycerate dehydrogenase, an enzyme of serine biosynthesis, and serine hydroxymethyltransferase, serine dehydratase and serine aminotransferase, which are competing enzymes of serine utilization, were assayed in human colon carcinomas from patients and in transplantable rat sarcomas. "
4.	Primary Hyperoxaluria (Oxaluria, Primary) 05/15/1991 - "Primary hyperoxaluria type I due to a point mutation of T to C in the coding region of the serine:pyruvate aminotransferase gene." 05/15/1991 - "cDNA clones for serine:pyruvate aminotransferase (SPT, alternative name: alanine:glyoxylate aminotransferase) were obtained from a cDNA library constructed from the liver of a primary hyperoxaluria type I (PH1) case in which the SPT activity was approximately one-hundredth that in control liver. "
5.	Carcinoma (Carcinomatosis) 01/01/1988 - "The activities of 3-phosphoglycerate dehydrogenase, an enzyme of serine biosynthesis, and serine hydroxymethyltransferase, serine dehydratase and serine aminotransferase, which are competing enzymes of serine utilization, were assayed in human colon carcinomas from patients and in transplantable rat sarcomas. "

Related Drugs and Biologics

1.	Enzymes
2.	Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)
3.	L-Serine Dehydratase (Serine Dehydratase)
4.	Serine (L-Serine)
5.	Alanine (L-Alanine)
6.	glyoxylic acid (glyoxylate)
7.	serine-pyruvate aminotransferase
8.	Phosphoglycerate Dehydrogenase (Dehydrogenase, Phosphoglycerate)
9.	Small Interfering RNA (siRNA)
10.	Pyruvic Acid (Pyruvate)