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serine carboxypeptidase

Also Known As:

serine carboxypeptidase II

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Exopeptidases: 68
        Carboxypeptidases: 268
        serine carboxypeptidase: 9

Experts

1.	Hinek, Aleksander: 2 articles (01/2017 - 01/2009)
2.	Pshezhetsky, Alexey V: 2 articles (01/2017 - 01/2009)
3.	Lübke, Torben: 1 article (01/2017)
4.	Pan, Xuefang: 1 article (01/2017)
5.	Wang, Yanting: 1 article (01/2017)
6.	Cordero-Pérez, Paula: 1 article (09/2015)
7.	Escobedo-Villarreal, Miguel Mariano: 1 article (09/2015)
8.	Gamboa-Esparza, Mariana: 1 article (09/2015)
9.	Mercado-Moreira, Amanda Berenice: 1 article (09/2015)
10.	Muñoz-Espinosa, Linda Elsa: 1 article (09/2015)

Related Diseases

1.	Infections 09/01/2015 - "The 5 proteins with higher scores in graft rejection were: alpha-1-microglobulin, 5'-nucleotidase cytosolic III, retinol-binding protein 4, membrane protein palmitoylated 4, and serine carboxypeptidase, while post-transplant infections were: mitochondrial acetyl-coenzyme A synthetase, putative adenosyl homocysteinase 2, zinc finger protein GLIS1, putative protein FAM157B, and zinc finger protein 615. " 07/17/2014 - "The expression patterns of 86 selected fungal genes over 7 days of infection of Douglas-fir were examined using real-time PCR, and those significantly up-regulated included rhamnogalacturonan acetylesterase, 1,4-benzoquinone reductase, a cyclophilin, a glucoamylase, 3 hydrophobins, a lipase, a serine carboxypeptidase, a putative Ran-binding protein, and two unknown putatively secreted proteins called 1 J04 and 2 J12. "
2.	Hypertension (High Blood Pressure) 01/01/2017 - "We have previously established that ET-1 can be degraded in vivo by two lysosomal/secreted serine carboxypeptidases, Cathepsin A (CathA) and Serine Carboxypeptidase 1 (Scpep1) and that gene-targeted CathAS190A /Scpep1-/- mice, deficient in CathA and Scpep1 have a prolonged half-life of circulating ET-1 associated with systemic hypertension. " 06/01/2010 - "Prolylcarboxypeptidase (PrCP) is a lysosomal serine carboxypeptidase that cleaves a variety of C-terminal amino acids adjacent to proline and has been implicated in diseases such as hypertension and obesity. "
3.	Neuraminidase deficiency with beta-galactosidase deficiency 06/01/1991 - "It was concluded that this enzyme deficiency is closely connected to the genetic defect of "protective protein." Further characterization with various protease inhibitors indicated that the enzyme deficient in galactosialidosis cells is a serine carboxypeptidase with histidine and cysteine residues at or near the active site." 01/01/2009 - "The major lysosomal serine carboxypeptidase A (cathepsin A [CathA]), also known as protective protein, activates and stabilizes two other lysosomal enzymes, beta-galactosidase and neuraminidase/sialidase 1. Genetic deficiency of CathA (galactosialidosis) causes the lysosomal storage of sialylated glycoconjugates and leads to a multiorgan pathology. "
4.	Disease Resistance 08/01/2009 - "A serine carboxypeptidase-like acyltransferase is required for synthesis of antimicrobial compounds and disease resistance in oats."
5.	Central Nervous System Protozoal Infections (Meningoencephalitis, Protozoal) 10/13/2022 - "In Silico Structural Analysis of Serine Carboxypeptidase Nf314, a Potential Drug Target in Naegleria fowleri Infections."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Cathepsin A
3.	Enzymes
4.	Cyclophilin A
5.	5'-Nucleotidase (5' Nucleotidase)
6.	Vitamin A (Retinol)
7.	Serine (L-Serine)
8.	Protease Inhibitors (Protease Inhibitor)
9.	Proline (L-Proline)
10.	Neuraminidase (Sialidase)