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retinyl methyl ether
RN given refers to (all-E)-isomer
Also Known As:
2-(9-methoxy-3,7-dimethyl-1,3,5,7-nonatetraenyl)-1,3,3-trimethylcyclohexene
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
Carotenoids: 4095
Retinoids: 5957
Vitamin A: 9071
retinyl methyl ether: 4
Diterpenes: 1470
Vitamin A: 9071
retinyl methyl ether: 4
Cyclic Hydrocarbons: 97
Alicyclic Hydrocarbons: 1
Cycloparaffins: 6
Cyclohexanes: 3
Cyclohexenes: 4
Carotenoids: 4095
Retinoids: 5957
Vitamin A: 9071
retinyl methyl ether: 4
Acyclic Hydrocarbons
Alkenes: 265
Polyenes: 164
Carotenoids: 4095
Retinoids: 5957
Vitamin A: 9071
retinyl methyl ether: 4
Biological Factors: 2472
Biological Pigments: 1
Carotenoids: 4095
Retinoids: 5957
Vitamin A: 9071
retinyl methyl ether: 4
Related Diseases
1.
Breast Neoplasms (Breast Cancer)
08/15/1997 - "
Retinyl methyl ether (RME) is known to prevent the development of mammary cancer.
"
02/01/1977 - "
Retinyl methyl ether also markedly increased the latent period for appearance of mammary cancers.
"
02/01/1977 - "
Inhibition of mammary cancer by retinyl methyl ether.
"
08/15/1997 - "
Retinyl methyl ether down-regulates activator protein 1 transcriptional activation in breast cancer cells.
"
01/01/1997 - "
It had been demonstrated previously that retinyl methyl ether (RME) can suppress carcinogen-induced mammary cancers in vivo.
"
2.
Neoplasms (Cancer)
02/01/1977 - "
Daily feeding of the synthetic retinoid, retinyl methyl ether, beginning one week after the oral administration of 7,12-dimethylbenz(a)anthracene to female Sprague-Dawley rats, inhibited the incidence of mammary cancer and diminished the number of mammary tumors, both malignant and benign, caused by 7,12-dimethylbenz(a)anthracene.
"
06/14/1996 - "
Retinyl methyl ether (RME) which prevents cancers of the rat mammary gland, binds to cellular retinol-binding protein and serum retinol-binding protein but not to cellular retinoic acid-binding protein or to the nuclear retinoid receptors, RARs/RXRs.
"
3.
Weight Gain
02/01/1977 - "
Retinyl methyl ether caused no evident toxicity and did not affect weight gain in these experiments.
"
Related Drugs and Biologics
1.
Retinoids
2.
Cellular Retinol-Binding Proteins
3.
Transcription Factor AP-1 (Transcription Factor AP 1)
4.
9,10-Dimethyl-1,2-benzanthracene
5.
Tretinoin (Retinoic Acid)
6.
Retinol-Binding Proteins (Retinoid Binding Proteins)
7.
Carrier Proteins (Binding Protein)
8.
Carcinogens
Related Therapies and Procedures
1.
Oral Administration