Bolton-Hunter reagent

RN given refers to 3-iodophenyl cpd

Also Known As:

Bolton-Hunter reagent, 125I-labeled; N-hydroxysuccinimide iodo-p-hydroxyphenylpropionate; iodo-p-hydroxyphenylpropionic acid N-hydroxysuccinimide ester

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Imides: 79
  - Succinimides: 11
    - Bolton-Hunter reagent: 4
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - Succinimides: 11
        Bolton-Hunter reagent: 4

Experts

1.	Ikekita, M: 1 article (05/2002)
2.	Kawakita, Y: 1 article (05/2002)
3.	Kojima, S: 1 article (05/2002)
4.	Shimura, N: 1 article (05/2002)
5.	Sogawa, Y: 1 article (05/2002)
6.	Yamazaki, N: 1 article (05/2002)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1983 - "A human lung tumor-associated antigen, previously purified to apparent homogeneity from an extract of a small cell tumor, was radioiodinated with Bolton-Hunter reagent for use in a competitive protein-binding radioimmunoassay. " 05/01/2002 - "Radioiodination of glycoprotein-conjugated liposomes by using the Bolton-Hunter reagent and biodistribution in tumor-bearing mice."
2.	Crohn Disease (Crohn's Disease) 09/01/1981 - "We also performed reverse experiments by iodination of the colonic mucosal extracts with Bolton-Hunter reagent and incubating them with several preparations of CCA-IgG. Mucosal extracts of colon from 3 patients with ulcerative colitis bound significantly with CCA-IgG when compared with the identical extracts from 3 patients with Crohn's disease, 3 with a normal colon (p less than 0.005), and with the control human IgG (p less than 0.025). "
3.	Ulcerative Colitis 09/01/1981 - "We also performed reverse experiments by iodination of the colonic mucosal extracts with Bolton-Hunter reagent and incubating them with several preparations of CCA-IgG. Mucosal extracts of colon from 3 patients with ulcerative colitis bound significantly with CCA-IgG when compared with the identical extracts from 3 patients with Crohn's disease, 3 with a normal colon (p less than 0.005), and with the control human IgG (p less than 0.025). "
4.	Breast Neoplasms (Breast Cancer) 01/01/1988 - "Binding to the breast cancer cell line, MCF-7, of native MAb DF3 was compared to that of MAb DF3 exposed to different concentrations of Iodogen or Bolton-Hunter reagent. "

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