pyrimidine phosphoribosyltransferase

pyrimidine monophosphate & pyrophosphate gives pyrimidine & phosphoribosyl pyrophosphate; acts with uracil, orotic acid or fluorouracil

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

1.	Neoplasms (Cancer) 10/01/1985 - "The activity of the alternative pathway to FUMP with a pyrimidine phosphoribosyltransferase [FUra + 1-pyrophosphoribosyl-5-phosphate (PPRP)] was approximately 15 to 17 nmoles/mg protein/hr in bone marrow from mice and rats and ranged from 28 to 47 nmoles/mg protein/hr in tumor tissues. " 03/01/1982 - "These findings have relevance to the treatment of human cancer, since pyrimidine phosphoribosyltransferase, thymidine kinase, or uridine kinase could be assayed in tumor biopsies in order to predict whether the fluoropyrimidines would be effective in individual patients."
2.	Leukemia 07/10/1975 - "Studies on a pyrimidine phosphoribosyltransferase from murine leukemia P1534J. " 11/01/1972 - "Some properties of a pyrimidine phosphoribosyltransferase from murine leukemia cells."