|1.||Ustok, Fatma Isik: 1 article (10/2014)|
|2.||Huntington, James A: 1 article (10/2014)|
|3.||Pomowski, Anja: 1 article (10/2014)|
|4.||Chan, Howard H W: 1 article (01/2013)|
|5.||Chan, Anthony K C: 1 article (01/2013)|
|6.||Chander, Ankush: 1 article (01/2013)|
|7.||Stevic, Ivan: 1 article (01/2013)|
|8.||Berry, Leslie R: 1 article (01/2013)|
|9.||Charania, Roseleen: 1 article (12/2011)|
|10.||Holter, Jennifer: 1 article (12/2011)|
|1.||Venous Thrombosis (Deep-Vein Thrombosis)
01/01/1990 - "Our results indicate that these tumor cells can readily assemble a functional cell surface prothrombinase complex that may be important in fibrin deposition associated with the growth and metastatic progression of these, and perhaps, other tumors."
01/01/2005 - "However, few studies correlate this type of cancer with formation of the prothrombinase complex, which is responsible for conversion of prothrombin into thrombin in the coagulation system. "
|3.||Melanoma (Melanoma, Malignant)
01/01/2005 - "The aim of this study was to investigate the assembly and regulation of prothrombinase complex on the murine melanoma cell line, B16F10. "
01/01/2005 - "Assembly and regulation of prothrombinase complex on B16F10 melanoma cells."
01/01/2005 - "Our data demonstrate that B16F10 melanoma cells generate thrombin by promoting assembly of the prothrombinase complex. "
12/03/1990 - "While melanoma cells served as a suitable surface for prothrombinase complex formation, folate deficiency did not alter this membrane function, suggesting that the membrane changes associated with folate deficiency are relatively specific."
01/01/2013 - "Overt exposure of phosphatidylserine on surfaces of RBCs provide docking sites for formation of the prothrombinase complex, which further aids in amplification of coagulation leading to subsequent thrombosis. "
10/01/2014 - "The balance between bleeding and thrombosis depends on the amount of thrombin produced, and this in turn depends on the function of the prothrombinase complex. "
03/01/2002 - "Activation of the prothrombinase complex, which catalyzes the formation of thrombin from prothrombin, is crucial for the (patho)physiological processes of hemostasis and thrombosis. "
11/01/1997 - "A synergic interaction between the prothrombin 20210 GA genotype and the factor V Leiden mutation, both potentially affecting the prothrombinase complex, was suggested by the early onset of thrombosis (median age 22 years) in doubly heterozygous patients. "
04/01/2000 - "The available evidence suggests strongly that intravascular thrombosis is mediated predominantly by tissue-factor and its activation of factor X, which in the presence of factor Va, calcium, and phospholipid (prothrombinase complex) effectively converts prothrombin to thrombin. "
|5.||Vascular System Injuries
12/01/2011 - "By formation of a highly active membrane-bound prothrombinase complex, these PLTs represent an important step in the coagulation cascade as a consequence of their ability to generate thrombin at the site of vascular injury. "
12/08/2006 - "Incorporation of prothrombin into the prothrombinase complex is essential for rapid thrombin generation at sites of vascular injury. "
|2.||Prothrombin (Factor II)
|5.||Thromboplastin (Tissue Factor)
|7.||Folic Acid (Vitamin M)
|9.||Factor X (Stuart Factor)