|1.||Aksoy, Nurten: 26 articles (10/2015 - 01/2007)|
|2.||Celik, Hakim: 11 articles (07/2015 - 01/2007)|
|3.||Forlino, Antonella: 8 articles (03/2015 - 10/2002)|
|4.||Aslan, Mehmet: 6 articles (07/2015 - 01/2007)|
|5.||Camuzcuoglu, Hakan: 6 articles (04/2015 - 10/2009)|
|6.||Rossi, Antonio: 6 articles (03/2015 - 06/2005)|
|7.||Besio, Roberta: 5 articles (03/2015 - 05/2010)|
|8.||Palka, Jerzy: 5 articles (01/2015 - 11/2002)|
|9.||Surazynski, Arkadiusz: 5 articles (01/2015 - 11/2002)|
|10.||Miltyk, Wojciech: 5 articles (01/2015 - 04/2005)|
09/18/2011 - "Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis."
01/01/1988 - "Biochemical studies on prolidase in sera from control, patients with prolidase deficiency and their mother."
03/01/1982 - "Biochemical studies on human prolidase (EC 22.214.171.124) and prolidase deficiency are described. "
03/01/2015 - "Mutations in the prolidase gene cause prolidase deficiency (PD), a rare recessive disorder. "
01/01/2013 - "Prolidase deficiency (PD) is an intractable loss of function disease, characterized by mutations in the prolidase gene. "
10/01/2012 - "The aim of this study is to measure prolidase activity as a marker of treatment and diagnosis in an experimental lung fibrosis animal model. "
01/01/2010 - "Several studies have shown increased prolidase activity in fibrosis, though controversy persists. "
06/14/2015 - "Furthermore the prolidase levels in HCC patients showed a significant difference compared with patients with cirrhosis (P < 0.001). "
09/01/2013 - "Prolidase levels were evaluated in three different groups, and its correlations with fibrosis were investigated. "
10/01/2012 - "The fibrosis scores and the prolidase activity were significantly enhanced by BLM stimulation. "
|3.||Melanoma (Melanoma, Malignant)
11/01/2008 - "Beside its intracellular functions, prolidase has an antitoxic effect against some organophosphorus molecules, can be used in dietary industry as bitterness reducing agent and recently has been used as target enzyme for specific melanoma prodrug activation. "
01/01/2009 - "Previously, prolidase has been linked to collagen metabolism and more recently is being associated with melanoma. "
01/01/2009 - "Increased prolidase activity in melanoma cell lines has lead investigators to create cancer prodrugs targeting this enzyme. "
07/01/2007 - "Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma."
01/01/2005 - "Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs."
02/01/2013 - "Ectopic pregnancy may be associated with increased serum prolidase activity and oxidative stress, and this association may help to provide a better understanding about the pathogenesis of ectopic pregnancy."
02/01/2013 - "Total antioxidant capacity levels were lower in the ectopic pregnancy group than the healthy group (p < 0.018), whereas total oxidant status, oxidative stress index and prolidase activity were higher (p < 0.05). "
02/01/2013 - "To determine the oxidative status and serum prolidase activity in tubal ectopic pregnancy and to see if there was any association between them. "
02/01/2013 - "Oxidative status and serum prolidase activity in tubal ectopic pregnancy."
11/01/2002 - "In pancreatitis tissue, an increase in collagen content, collagenolytic activity and beta 1 integrin expression were accompanied by significant decrease (about 2-fold) in prolidase activity and marked decrease in its expression, compared to normal pancreas. "
11/01/2002 - "We investigated whether prolidase activity may reflect disturbances of collagen metabolism in human pancreatitis and pancreatic cancer. "
|5.||1- (2- (4- benzyl- 4- hydroxypiperidin- 1- yl)ethyl)- 3- (2- methylquinolin- 4- yl)urea
|7.||Biological Markers (Surrogate Marker)
|10.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|2.||Drug Therapy (Chemotherapy)
|3.||Enzyme Replacement Therapy
|5.||Renal Dialysis (Hemodialysis)