lysosomal Pro-X carboxypeptidase

04/01/2020 - "Genetic association study of prolylcarboxypeptidase polymorphisms with susceptibility to essential hypertension in the Yi minority of China: A case-control study based on an isolated population."
09/15/1997 - "The human angiotensinase C gene (HUMPCP) maps to 11q14 within 700 kb of D11S901: a candidate gene for essential hypertension."
09/01/2013 - "Association of polymorphisms in prolylcarboxypeptidase and chymase genes with essential hypertension in the Chinese Han population."

07/01/2006 - "There is no published study on prolylcarboxypeptidase gene and preeclampsia. "
07/01/2006 - "Gene expression assays lent further support for the functional significance of prolylcarboxypeptidase in the etiology of preeclampsia."
07/01/2006 - "Our data showed that prolylcarboxypeptidase D allele coupled with chronic hypertension was associated with a significantly increased risk of preeclampsia in both black and non-black women. "
07/01/2006 - "Prolylcarboxypeptidase E112D (rs2298668) D allele along and jointly with chronic hypertension were associated with a significantly increased risk of preeclampsia. "
07/01/2006 - "Prolylcarboxypeptidase gene, chronic hypertension, and risk of preeclampsia."

01/01/2015 - "Prolylcarboxypeptidase gene expression in the heart and kidney: Effects of obesity and diabetes."
10/14/2010 - "Design and synthesis of prolylcarboxypeptidase (PrCP) inhibitors to validate PrCP as a potential target for obesity."
04/01/2010 - "Prolylcarboxypeptidase (PRCP) as a new target for obesity treatment."
07/01/2012 - "Plasma prolylcarboxypeptidase (angiotensinase C) is increased in obesity and diabetes mellitus and related to cardiovascular dysfunction."
06/01/2010 - "Prolylcarboxypeptidase (PrCP) is a lysosomal serine carboxypeptidase that cleaves a variety of C-terminal amino acids adjacent to proline and has been implicated in diseases such as hypertension and obesity. "

07/01/2006 - "We further compared the prolylcarboxypeptidase transcript levels in peripheral blood cells of 23 preeclamptic (30% with chronic hypertension) and 51 non-preeclamptic (6% with chronic hypertension) women 2 - 3 days after delivery. "
04/07/2011 - "Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis."
07/01/2006 - "Our data showed that prolylcarboxypeptidase D allele coupled with chronic hypertension was associated with a significantly increased risk of preeclampsia in both black and non-black women. "
07/01/2006 - "Prolylcarboxypeptidase E112D (rs2298668) D allele along and jointly with chronic hypertension were associated with a significantly increased risk of preeclampsia. "
07/01/2006 - "Prolylcarboxypeptidase gene, chronic hypertension, and risk of preeclampsia."

04/07/2011 - "Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis."
01/01/2012 - "Influence of a novel inhibitor (UM8190) of prolylcarboxypeptidase (PRCP) on appetite and thrombosis."
08/22/2013 - "Prolylcarboxypeptidase (PRCP) is associated with leanness, hypertension, and thrombosis. "