|1.||Zhang, Lei: 1 article (02/2010)|
|2.||Ma, Taotao: 1 article (02/2010)|
|3.||Lv, Xiongwen: 1 article (02/2010)|
|4.||Wang, Jianqing: 1 article (02/2010)|
|5.||Meng, Xiaoming: 1 article (02/2010)|
|6.||Li, Jun: 1 article (02/2010)|
|7.||Huang, Cheng: 1 article (02/2010)|
|8.||Dhanraj, Prema: 1 article (07/2008)|
|9.||Margaret Shanthi, F X: 1 article (07/2008)|
|10.||Ernest, Kalpana: 1 article (07/2008)|
10/15/1989 - "CSC-21K produced by tumor cells is isolated as a 1:1 molar complex with type IV procollagenase, as demonstrated by amino acid composition analysis. "
06/05/1991 - "Previous studies have shown that both normal cells and highly invasive tumor cells produce the 72-kd type IV procollagenase enzyme in a complexed form consisting of the proenzyme and a novel tissue inhibitor of metalloproteinases, TIMP-2. "
01/01/1989 - "Another hypothesis is that PA may activate procollagenase to collagenase, which digests collagen to facilitate tumor growth. "
12/19/1990 - "Histochemical analysis using rabbit antiserum raised against the synthetic peptides of 72-kd procollagenase type IV showed type IV collagenase in the intracecal tumors; human colon carcinoma growing SC, however, were not stained significantly. "
01/01/1992 - "These results indicated that bestatin may inhibit tumor cell invasion through a mechanism involving its inhibitory action on aminopeptidases in tumor cells, suggesting that the aminopeptidase may partly be associated with the conversion of a latent form of type IV procollagenase to an active form or the secretion of the collagenases from tumor cells."
01/01/1991 - "Purification of a procollagenase-activator present in medium of cultured guinea pig carrageenin granuloma."
01/01/1991 - "In this study we have purified by DEAE-cellulose, Ultrogel AcA-44, and zinc chelate sepharose chromatographies, a procollagenase-activator from the culture medium of the guinea pig carrageenin granuloma model. "
12/01/1997 - "We attempted to study the possible relationships between neutrophil-type procollagenase/pro-matrix metalloproteinase (MMP-8) and the serine proteinases plasmin, cathepsin G and tryptase in bronchiectasis. "
12/01/1997 - "Potentiative effects of neutral proteinases in an inflamed lung: relationship of neutrophil procollagenase (proMMP-8) to plasmin, cathepsin G and tryptase in bronchiectasis in vivo."
04/01/2002 - "In order to ascertain whether there is a relationship between Endo180 binding and procollagenase 3 activation, we have compared procollagenase 3 activation by an HT1080 fibrosarcoma cell line overexpressing MT1 MMP, without and with overexpression of Endo180. "
07/15/1992 - "The precursor of matrix metalloproteinase 9 (proMMP-9), also known as '92 kDa progelatinase/type IV procollagenase', was purified from the conditioned medium of U937 monocytic leukaemia and HT1080 fibrosarcoma cell lines stimulated with phorbol 12-myristate 13-acetate. "
02/15/2002 - "Nobiletin inhibited the tumor-invasive activity of human fibrosarcoma HT-1080 cells in the Matrigel model, whereas a similar inhibition was observed upon exogenously adding tissue inhibitors of metalloproteinases (TIMPs)-1 and -2. The gene expression and production of pro-matrix metalloproteinase 9 (proMMP-9)/progelatinase B and proMMP-1/interstitial procollagenase were specifically suppressed by nobiletin in 12-O-tetradecanoylphorbol 13-acetate-stimulated HT-1080 cells. "
11/01/1986 - "Culturing the calvaria for 2 days with parathyroid hormone (PTH) increases their procollagenase content up to 3-fold and induces bone resorption. "
05/16/1979 - "Collagenase, procollagenase and bone resorption. "
07/01/1988 - "The participation of collagenase in bone resorption has been investigated by assaying the procollagenase extracted from fetal mouse calvaria cultured under a variety of conditions, and by evaluating its ability to degrade bone collagen. "
|1.||Tissue Inhibitor of Metalloproteinases (TIMP)
|3.||Serine Proteases (Serine Protease)
|6.||Tissue Inhibitor of Metalloproteinase-2