|1.||Jackson, Patricia L: 5 articles (10/2015 - 04/2008)|
|2.||Tenorio-Laranga, Jofre: 5 articles (01/2015 - 01/2010)|
|3.||García-Horsman, J Arturo: 5 articles (01/2015 - 01/2010)|
|4.||Khlebnikova, N N: 5 articles (10/2013 - 11/2006)|
|5.||Zolotov, N N: 5 articles (10/2013 - 11/2006)|
|6.||Krupina, N A: 5 articles (10/2013 - 11/2006)|
|7.||Blalock, J Edwin: 4 articles (10/2015 - 04/2008)|
|8.||Gaggar, Amit: 4 articles (10/2015 - 04/2008)|
|9.||Männistö, Pekka T: 4 articles (05/2014 - 12/2006)|
|10.||Bogdanova, N G: 4 articles (10/2013 - 11/2006)|
|1.||Celiac Disease (Celiac Sprue)
12/20/2005 - "Fermentation, purification, formulation, and pharmacological evaluation of a prolyl endopeptidase from Myxococcus xanthus: implications for Celiac Sprue therapy."
09/01/2005 - "No genetic association of the human prolyl endopeptidase gene in the Dutch celiac disease population."
09/27/2002 - "The peptide could be detoxified in in vitro and in vivo assays by exposure to a bacterial prolyl endopeptidase, suggesting a strategy for oral peptidase supplement therapy for Celiac Sprue."
09/01/2005 - "Oral administration of a bacterial prolyl-endopeptidase (PEP) therefore was proposed as a treatment for celiac disease. "
03/01/2003 - "[Oral administration of prolyl-endopeptidase: a rational treatment for celiac disease?]."
10/01/1989 - "A potent prolyl endopeptidase inhibitor, Z-thiopro-thiazolidine, and 2 novel pyrrolidone derivatives, p-chlorobenzyl-2-pyrrolidone-5-carboxylate and N-(2-pyridylmethyl)-2-pyrrolidone-5-carboxamide, improved the acquisition of the passive avoidance response in the ischemia-induced amnesic models."
05/14/1999 - "We investigated the effects of the prolyl endopeptidase inhibitors 1-[1-(Benzyloxycarbonyl)-L-prolyl]prolinal (Z-Pro-Prolinal) and N-benzyloxycarbonyl-thioprolyl-thioprolinal-dimethylaceta l (ZTTA) on delayed neuronal death induced by four-vessel-occlusion transient ischemia in rats. "
06/01/2014 - "Recent studies have indicated that specific prolyl oligopeptidase (PREP) inhibitors can modulate inflammation, angiogenesis and neurodegeneration. "
07/01/1992 - "Prolyl endopeptidase purified from granulomatous inflammation in mice."
01/01/2015 - "The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients."
01/01/2014 - "Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation."
07/01/1992 - "Activity of prolyl endopeptidase (EC 126.96.36.199) which hydrolyses the Pro7-Phe8 bond in angiotensin II has been found to elevate in experimentally produced granulomatous inflammation in liver and skin. "
|5.||Amnesia (Dissociative Amnesia)
02/25/2005 - "Prolyl oligopeptidase is implicated in the metabolism of neuropeptides and is involved in amnesia and depression. "
12/01/1992 - "Protective effect of eurystatins A and B, new prolyl endopeptidase inhibitors, on scopolamine-induced amnesia in rats."
12/01/1992 - "Eurystatins A and B, which are produced by Streptomyces eurythermus R353-21, potently inhibited Flavobacterium prolyl endopeptidase (PED) with IC50 values of 0.004 and 0.002 micrograms/ml, respectively, while no inhibition was observed against another 5 proteases, even at 100 micrograms/ml. The protective effect of eurystatins A and B against scopolamine (3 mg/kg, i.p.)-induced amnesia in rats was evaluated by the step-through one-trial passive avoidance method. "
05/01/1996 - "Its action on vasopressin has been proposed as the underlying mechanism accounting for the ability of inhibitors of prolyl oligopeptidase to reverse scopolamine-induced amnesia in rats. "
02/01/2002 - "Prolyl oligopeptidase is involved in amnesia, depression and blood pressure control, dipeptidyl peptidase IV in type 2 diabetes and oligopeptidase B in trypanosomiasis."
|6.||prolyl oligopeptidase (prolyl endopeptidase)
|8.||Peptide Hydrolases (Proteases)
|9.||Proteins (Proteins, Gene)
|10.||Serine Proteases (Serine Protease)
|4.||Surgical Instruments (Clip)