|1.||Wang, Zhao-Qi: 5 articles (12/2010 - 03/2005)|
|2.||Cuzzocrea, Salvatore: 5 articles (01/2007 - 06/2004)|
|3.||Zhang, Jie: 4 articles (01/2007 - 06/2004)|
|4.||Genovese, Tiziana: 3 articles (01/2007 - 06/2004)|
|5.||Massuda, Edmond: 3 articles (01/2007 - 06/2004)|
|6.||Di Paola, Rosanna: 3 articles (01/2007 - 06/2004)|
|7.||Li, Jia-He: 3 articles (01/2007 - 06/2004)|
|8.||Mazzon, Emanuela: 3 articles (01/2007 - 03/2005)|
|9.||Fauzee, Nilufer Jasmine Selimah: 2 articles (04/2012 - 12/2010)|
|10.||Pan, Juan: 2 articles (04/2012 - 12/2010)|
03/01/2012 - "Inhibition of poly(ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells."
09/01/2013 - "Poly (ADP-ribose) glycohydrolase (PARG), which was discovered during studies on DNA damage study and in inflammation research, is an attractive target protein in current cancer research. "
12/01/2010 - "A lot of effort has been put in by researchers and scientists over decades to find drugs helpful in the treatment of cancers for the benefit of patients--the latest being the Poly ADP-ribose polymerase (PARP) and the Poly ADP-ribose glycohydrolase (PARG) inhibitors. "
04/01/2012 - "Poly ADP-ribose polymerase (PARP) which is closely related to Poly ADP-ribose glycohydrolase (PARG) has already been thoroughly investigated in both experimental and clinical cancer trials compared to the latter. "
07/15/1992 - "Oligomeric ellagitannins (nobotanins B, E, and K) were found to be potent inhibitors of poly(ADP-ribose) glycohydrolase purified from mouse mammary tumor 34I cells. "
|3.||Breast Neoplasms (Breast Cancer)
12/04/2009 - "Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells."
01/01/2012 - "Silencing of Apoptosis-Inducing factor and poly(ADP-ribose) glycohydrolase reveals novel roles in breast cancer cell death after chemotherapy."
12/15/2013 - "Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome."
01/01/2013 - "Outstandingly, here we demonstrate that the lack of poly(ADP-ribose) glycohydrolase activity in Vero and A549 host cells, achieved by chemical inhibition or iRNA, produces the reduction of the percentage of infected cells as well as the number of amastigotes per cell and trypomastigotes released, leading to a nearly complete abrogation of the infection process. "
01/01/2013 - "Host cell poly(ADP-ribose) glycohydrolase is crucial for Trypanosoma cruzi infection cycle."
08/01/2012 - "Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase."
08/01/1988 - "We postulate that hyperthermia alters poly(ADP-ribose) glycohydrolase activity by two mechanisms, an irreversible thermal denaturation of the enzyme and a reversible metabolic alteration. "
08/01/1988 - "The results argue that poly(ADP-ribose) glycohydrolase activity is reversibly altered by hyperthermia. "
08/01/1988 - "Changes in poly(ADP-ribose) glycohydrolase activity can account in full for the observed alterations of poly(ADP-ribose) metabolism that occur following hyperthermia."
08/01/1988 - "The effects of supranormal temperature on the activity of poly(ADP-ribose) glycohydrolase were studied by assaying the enzyme in cell extracts derived from cells subjected to hyperthermia and comparing with extracts that were heated in vitro. "
|1.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
|2.||Poly Adenosine Diphosphate Ribose
|3.||Apoptosis Inducing Factor
|4.||Tannins (Tannic Acid)
|5.||Caspase 3 (Caspase-3)
|9.||Messenger RNA (mRNA)
|1.||Drug Therapy (Chemotherapy)