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phosphatidylserine decarboxylase

Also Known As:

phosphatidylserine decarboxylase 2

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Lyases: 637
    - Carbon-Carbon Lyases
      - Carboxy-Lyases: 620
        phosphatidylserine decarboxylase: 8

Experts

1.	Vance, Jean E: 2 articles (01/2019 - 12/2005)
2.	Bernier, Francois P: 1 article (01/2019)
3.	Bhatia-Kiššová, Ingrid: 1 article (01/2019)
4.	Blancard, Corinne: 1 article (01/2019)
5.	Camougrand, Nadine: 1 article (01/2019)
6.	Care4Rare Canada Consortium: 1 article (01/2019)
7.	Claypool, Steven M: 1 article (01/2019)
8.	Cornish, Adam J: 1 article (01/2019)
9.	Cougouilles, Elodie: 1 article (01/2019)
10.	Goedhart, Caitlin M: 1 article (01/2019)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 08/01/2023 - "Phosphatidylserine decarboxylase downregulation in uric acid‑induced hepatic mitochondrial dysfunction and apoptosis." 12/02/2005 - "Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects."
2.	Starvation 01/01/2019 - "Through different approaches, we show that Psd1, the mitochondrial phosphatidylserine decarboxylase, is involved in mitophagy induction only after nitrogen starvation, whereas Psd2, which is located in vacuole, Golgi and endosome membranes, is required preferentially for mitophagy induction in the stationary phase of growth but also to a lesser extent for nitrogen starvation-induced mitophagy. " 01/01/2019 - "The mitochondrial phosphatidylserine decarboxylase Psd1 is involved in nitrogen starvation-induced mitophagy in yeast."
3.	Retinal Degeneration 08/11/2010 - "Light-dependent retinal degeneration in the Drosophila visual system is caused by the knockdown or mutation of autophagy-essential components, such as autophagy-related protein 7 and 8 (atg-7/atg-8), or genes essential for PE (phosphatidylethanolamine) biogenesis and autophagosome formation, including Phosphatidylserine decarboxylase (Psd) and CDP-ethanolamine:diacylglycerol ethanolaminephosphotransferase (Ept). "
4.	Parkinson Disease (Parkinson's Disease) 12/01/2014 - "We recently reported that knocking down the enzyme phosphatidylserine decarboxylase, which synthesizes the phospholipid phosphatidylethanolamine (PE) in mitochondria, perturbs the homeostasis of the human Parkinson disease (PD) protein α-synuclein (expressed in yeast or worms). "
5.	Neoplasms (Cancer) 01/01/2022 - "Previously, we found that despite its pro-apoptotic activity, SMAC/Diablo is overexpressed in cancer, and demonstrated that in cancer it possesses new essential and non-apoptotic functions that are associated with regulating phospholipid synthesis including modulating mitochondrial phosphatidylserine decarboxylase activity. "

Related Drugs and Biologics

1.	phosphatidylethanolamine
2.	Phospholipids (Phosphatides)
3.	Enzymes
4.	Synucleins
5.	Proteins (Proteins, Gene)
6.	Phosphatidylserines
7.	Nitrogen
8.	Ethanolaminephosphotransferase
9.	Diglycerides
10.	Autophagy-Related Protein 7