RN given refers to cpd with unknown MF; see also records for cremophor EL & cremophor A; polyoxyethylated castor oil
Also Known As:
chremofore; cremophor AP; cremophor RH 40; cremophor RH 40/60; cremophor WO-CE 5070; cremophor, O(beta)-isomer
Networked: 101 relevant articles (9 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Au, Jessie L-S: 4 articles (09/2015 - 11/2004)
2. Lu, Ze: 4 articles (09/2015 - 11/2004)
3. Wientjes, M Guillaume: 3 articles (09/2015 - 12/2013)
4. Tsai, Max: 3 articles (01/2014 - 11/2004)
5. Wang, Hongbo: 2 articles (01/2014 - 02/2013)
6. Tian, Jingwei: 2 articles (01/2014 - 02/2013)
7. Fu, Fenghua: 2 articles (01/2014 - 02/2013)
8. Scripture, Charity D: 2 articles (04/2006 - 06/2005)
9. Sparreboom, Alex: 2 articles (04/2006 - 06/2005)
10. Figg, William D: 2 articles (04/2006 - 06/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Carcinoma (Carcinomatosis)
09/01/2015 - "Preclinical studies show that TPM is less toxic and more effective against several IP metastatic tumors with different characteristics (fast vs. slow growing, porous vs. densely packed structures, wide-spread vs. solitary tumors, early vs. late stage, with or without peritoneal carcinomatosis or ascites), compared to the intravenous paclitaxel/Cremophor micellar solution that has been used off-label in previous IP studies. "
01/01/1993 - "Taxol, dissolved in cremophor/ethanol (50/50), followed by further dilution with saline, was successfully administered intravenously (IV) to mice bearing subcutaneously (SC) implanted murine Madison 109 lung carcinoma (M109), M5076 sarcoma, or seven different human tumor xenografts, including A431 vulva; A2780 ovarian; LX-1, H2981, and L2987 lung; and RCA and HCT-116 colon carcinomas. "
01/01/1996 - "The tumor model was an N-(4-[5-nitro-2-furyl]-2-thiazolyl) formamide (FANFT)-induced urothelial cell carcinoma transplanted into one hind leg of male Fischer 344 rats; isoBOSINC was delivered to the rats by intravenous injection of 0.50 mg/kg of body weight as a suspension either in 10% Tween 80 in saline (Tween) or 10% (Cremophor EL + propylene glycol) in saline (Cremophor). "
01/01/2008 - "The studies discussed here include the following: i) a phase I study of a chemotherapy doublet gemcitabine plus capecitabine, combined with a biologic doublet (bevacizumab plus erlotinib) in patients with advanced pancreatic adenocarcinoma (abstract #141); ii) a phase II study of gemcitabine, bevacizumab, and erlotinib in locally advanced and metastatic adenocarcinoma of the pancreas (abstract #151); iii) final results of the multicenter phase II study on gemcitabine, capecitabine, and bevacizumab in patients with advanced pancreatic cancer (abstract #198); iv) interim results from a phase II study of volociximab in combination with gemcitabine in patients with metastatic pancreatic cancer (abstract #142); v) a pilot study of combination chemotherapy with S-1 and irinotecan for advanced pancreatic cancer (abstract #155); vi) a multicenter phase II study of gemcitabine and S-1 combination chemotherapy in patients with unresectable pancreatic cancer (abstract #212); vii) a phase I/II study of PHY906 plus capecitabine in patients with advanced pancreatic carcinoma (abstract #260); and viii) the final results of a phase II trial of Genexol-PM(R), a novel cremophor-free, polymeric micelle formulation of paclitaxel in patients with advanced pancreatic cancer (abstract #269). "
4. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
5. Ascites

Related Drugs and Biologics

1. Paclitaxel (Taxol)
2. albumin-bound paclitaxel
3. 130-nm albumin-bound paclitaxel
4. Ethanol (Ethyl Alcohol)
5. Micelles
6. 1-phenyl-3,3-dimethyltriazene (PDT)
7. Cysteine (L-Cysteine)
8. gemcitabine
9. Platinum
10. Cisplatin (Platino)

Related Therapies and Procedures

1. Injections
2. Drug Therapy (Chemotherapy)
3. Combination Drug Therapy (Combination Chemotherapy)
4. Heterologous Transplantation (Xenotransplantation)
5. Intravenous Injections